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Tumor with the features of both squamous cell carcinoma and melanoma (melanocarcinoma). | LitMetric

Combined tumors of malignant melanoma (MM) and squamous cell carcinoma (SCC) are extremely rare and have unknown biological potential. Different theories of their development, including collision and dual/divergent differentiation, are proposed. Although some observations suggest an indolent course for such tumors, a case of MM metastasis was reported in a patient who initially presented with a combined MM-SCC tumor. Re-excisions of such tumors may show MM in situ and should be treated accordingly. Herein we present another case of a combined MM-SCC tumor in a 78 male patient with lentigo maligna seen after complete re-excision of the tumor.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439757PMC
http://dx.doi.org/10.4103/2229-5178.156422DOI Listing

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