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Establishment of a Genetic Transformation and Gene Editing Method by Floral Dipping in .
Plants (Basel)
October 2024
Lushan Botanical Garden, Jiangxi Province and Chinese Academy of Sciences, NO.9 Zhiqing Road, Jiujiang 332900, China.
Article Synopsis
- L. Webb ex Prantl is widely used in traditional medicine but lacks an effective genetic transformation system for research and application.
- This study presents a new, efficient method for genetic transformation that involves dipping inflorescences in a specific solution for 45 seconds, leading to successful plant transformations.
- The method also incorporates CRISPR/Cas9 for targeted genome editing, enabling the creation of mutant plants with a specific trait in just 2.5 months.
Cardiac Troponin to Adjudicate Subclinical Heart Failure in Diabetic Patients and a Murine Model of Metabolic Syndrome.
J Appl Lab Med
November 2024
Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, United States.
Background: Cardiovascular disease, kidney health, and metabolic disease (CKM) syndrome is associated with significant morbidity and mortality, particularly from congestive heart failure (CHF). Guidelines recommend measurement of cardiac troponin (cTn) to identify subclinical heart failure (HF) in diabetics/CKM. However, appropriate thresholds and the impact from routine screening have not been elucidated.
View Article and Find Full Text PDFChanges in Bone Mineral Density and Related Influencing Factors Assessed by Quantitative Computed Tomography in Maintenance Dialysis Patients.
J Coll Physicians Surg Pak
October 2023
Department of Radiology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Objective: To investigate the changes in volumetric bone mineral density (vBMD) assessed by quantitative computed tomography (QCT) in chronic kidney disease (CKD) patients on maintenance dialysis.
Study Design: Descriptive study. Place and Duration of the Study: Department of Radiology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China, from March to July 2022.
Patient-Specific Finite Element Modeling of the Whole Lumbar Spine Using Clinical Routine Multi-Detector Computed Tomography (MDCT) Data-A Pilot Study.
Biomedicines
June 2022
Department of Diagnostic and Interventional Neuroradiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.
(1) Background: To study the feasibility of developing finite element (FE) models of the whole lumbar spine using clinical routine multi-detector computed tomography (MDCT) scans to predict failure load (FL) and range of motion (ROM) parameters. (2) Methods: MDCT scans of 12 subjects (6 healthy controls (HC), mean age ± standard deviation (SD): 62.16 ± 10.
View Article and Find Full Text PDF[Factors Influencing Pneumococcal Vaccination-Induced Total IgG, IgG2, and IgA Levels in Vaccinated Splenectomized Patients].
Mikrobiyol Bul
January 2022
TOBB University of Economics and Technology Faculty of Medicine, Department of Medical Microbiology, Ankara, Turkey.
Article Synopsis
- The study examines the impact of splenectomy on the risk of infections, specifically looking at antibody levels after vaccination against Streptococcus pneumoniae.
- It involved three phases: assessing patient awareness of vaccination risks, measuring total Ig values among splenectomy patients, and vaccinating participants while analyzing their antibody responses.
- Results showed a significant lack of awareness about vaccination needs, with vaccinated patients having much higher antibody levels compared to unvaccinated, but no link was found between antibody levels and factors like age or gender.
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