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| http://dx.doi.org/10.5152/akd.2015.6175 | DOI Listing |
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Research progress in interventional therapy for acute intermediate-high-risk and high-risk pulmonary embolism.
J Thorac Dis
November 2024
Department of Vascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Article Synopsis
- Acute pulmonary embolism (APE) has a high mortality rate, particularly due to right heart failure in intermediate to high-risk patients, with current guidelines advocating for thrombolytic therapy in high-risk cases.
- Despite the recommendations, thrombolytic therapy is not commonly used due to risks like intracranial hemorrhage, and there's still uncertainty about the best treatment for intermediate-risk patients.
- New endovascular interventions, such as various types of thrombolysis and mechanical thrombectomy, show promise in improving heart function and reducing bleeding risks, prompting future research to better identify patients who would benefit from these treatments and enhance long-term outcomes.
Novel Challenges and Therapeutic Options for Pulmonary Embolism and Deep Vein Thrombosis.
J Pers Med
August 2024
Cardiology Division, Sant'Andrea Hostpital, 13100 Vercelli, Italy.
Acute pulmonary embolism (PE), often resulting from deep vein thrombosis (DVT), is the third most frequent cause of cardiovascular death and is associated with increasing incidence, causing considerable morbidity and mortality. This review aims to evaluate the efficacy, safety, and outcomes of treatment options in the management of acute PE and DVT, encompassing both established and emerging technologies, such as catheter-directed thrombolysis, aspiration thrombectomy, and other endovascular techniques. A comprehensive literature review was conducted, assessing clinical studies, trials, and case reports that detail the use of percutaneous interventions for PE and DVT and analyzing the advantages and disadvantages of each percutaneous system.
View Article and Find Full Text PDFUltrasound-Assisted Versus Standard Catheter-Directed Thrombolysis for Acute Pulmonary Embolism: Insights From National Inpatient Sample.
J Soc Cardiovasc Angiogr Interv
May 2024
Division of Cardiovascular Medicine, Gill Heart Institute, University of Kentucky, Lexington, Kentucky.
Background: Pulmonary embolism is one of the leading causes of morbidity and mortality in the United States. Catheter-directed therapies have emerged as a promising treatment for managing intermediate- and high-risk patients; however, data comparing standard catheter-directed thrombolysis (SCDT) and ultrasound-assisted thrombolysis (USAT) are limited. This study aimed to investigate trends, outcomes, and predictors of mortality of both modalities from a nationally representative sample.
View Article and Find Full Text PDFModern Treatment of Pulmonary Embolism (USCDT vs MT): Results From a Real-World, Big Data Analysis (REAL-PE).
J Soc Cardiovasc Angiogr Interv
January 2024
Center for Interventional Cardiovascular Care and Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York.
Background: Advanced therapies are increasingly utilized to treat pulmonary embolism (PE). A unique data platform allows access to electronic health record data for comparison of the safety of PE therapies.
Methods: All data from Truveta (Truveta, Inc) were analyzed (16 systems, 83,612,413 patients, 535,567 with PE).
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