We present a robot that enables high-content studies of alert adult Drosophila by combining operations including gentle picking; translations and rotations; characterizations of fly phenotypes and behaviors; microdissection; or release. To illustrate, we assessed fly morphology, tracked odor-evoked locomotion, sorted flies by sex, and dissected the cuticle to image neural activity. The robot's tireless capacity for precise manipulations enables a scalable platform for screening flies' complex attributes and behavioral patterns.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490062 | PMC |
| http://dx.doi.org/10.1038/nmeth.3410 | DOI Listing |
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