Collateral DNA damage produced by genome-editing drones: exception or rule?

Mol Cell

Laboratory of Genome Integrity, National Cancer Institute, NIH, Bethesda, MD 20892, USA. Electronic address:

Published: May 2015

In the recent issue of Nature Biotechnology, Frock et al. (2015) developed an elegant technique to capture translocation partners that can be utilized to determine off-target regions of genome-editing endonucleases as well as endogenous mutators at nucleotide resolution.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289255PMC
http://dx.doi.org/10.1016/j.molcel.2015.05.012DOI Listing

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