We report the synthesis and genetic encoding of a recently discovered post-translational modification, 2-hydroxyisobutyryl-lysine, to the genetic code of E. coli. The production of homogeneous proteins containing this amino acid will facilitate the study of modification in full-length proteins.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457286 | PMC |
http://dx.doi.org/10.1039/c5ob00283d | DOI Listing |
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