The aesthetics of designed products have become part of our life in modern society. This study explores the neural mechanisms of how aesthetic judgment and aesthetic emotion interplay during the appreciation of designed products that are commonly seen in daily life. Participants were 30 college students, and the stimuli were 90 pictures of everyday designed products. Based on an event-related paradigm, the findings of this study suggest that there are associative and dissociative neutral mechanisms underlying different types of aesthetic judgment and aesthetic emotion. The study identified the following main findings: (a) normative beauty and subjective beauty both involved the left anterior cingulate cortex (ACC); (b) subjective beauty and positive emotion both involved the right ACC; (c) subjective beauty and negative emotion both involved the precuneus; (d) subjective ugliness and negative emotion both involved the right inferior frontal gyrus; (e) subjective ugliness alone additionally activated the insula; and (f) subjective beauty alone additionally activated the caudate. The findings in this study shed light on complex but ordinary processes of aesthetic appreciation.
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http://dx.doi.org/10.1016/j.neuropsychologia.2015.05.010 | DOI Listing |
Am J Sports Med
January 2025
Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Background: Selective androgen receptor modulators (SARMs) are small-molecule compounds that exert agonist and antagonist effects on androgen receptors in a tissue-specific fashion. Because of their performance-enhancing implications, SARMs are increasingly abused by athletes. To date, SARMs have no Food and Drug Administration approved use, and recent case reports associate the use of SARMs with deleterious effects such as drug-induced liver injury, myocarditis, and tendon rupture.
View Article and Find Full Text PDFAdv Sci (Weinh)
January 2025
Information Materials and Intelligent Sensing Laboratory of Anhui Province, Key Laboratory of Structure and Functional Regulation of Hybrid Materials of Ministry of Education, Institutes of Physical Science and Information Technology, Anhui University, 111 Jiu Long Road, Hefei, 230601, China.
Unipolar barrier architecture is designed to enhance the photodetector's sensitivity by inducing highly asymmetrical barriers, a higher barrier for blocking majority carriers to depressing dark current, and a low minority carrier barrier without impeding the photocurrent flow through the channel. Depressed dark current without block photocurrent is highly desired for uncooled Long-wave infrared (LWIR) photodetection, which can enhance the sensitivity of the photodetector. Here, an excellent unipolar barrier photodetector based on multi-layer (ML) graphene (G) is developed, WSe, and PtSe (G-WSe-PtSe) van der Waals (vdW) heterostructure, in which extremely low dark current of 1.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Agricultural Engineering, Kongunadu College of Engineering and Technology, Trichy, Tamil Nadu, India.
This study investigates the enhancement of solar cell efficiency using nanofluid cooling systems, focusing on citrate-stabilized and PVP-stabilized silver nanoparticles. Traditional silicon-based and perovskite solar cells were examined to assess the impact of these nanofluids on efficiency improvement and thermal management. A Central Composite Design (CCD) was employed to vary nanoparticle concentration (0.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Floriculture, Ornamental Horticulture and Garden Design, Faculty of Agriculture (El-Shatby), Alexandria University, Alexandria, 21545, Egypt.
Natural extracts as biostimulants have the potential to enhance the productivity and growth of many medicinal and aromatic plants. This study aimed to enhance the growth, and essential oil (EO) content, as well as composition of Lavandula latifolia Medik. by using Malva parviflora L.
View Article and Find Full Text PDFNat Commun
January 2025
CIRI, Centre International de Recherche en Infectiologie Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, F-69007, Lyon, France.
Prime Editing can rewrite genes in living cells by allowing point mutations, deletions, or insertion of small DNA sequences with high precision. However, its safe and efficient delivery into human stem cells remains a technical challenge. In this report, we engineer Nanoscribes, virus-like particles that encapsidate ribonucleoprotein complexes of the Prime Editing system and allow their delivery into recipient cells.
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