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Urinary oxidative stress biomarkers in nephrotoxicity induced by PM in a rat model.
Inhal Toxicol
January 2025
Departamento de Toxicología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Mexico City, Mexico.
Objective: The present study evaluated urinary oxidative stress (OxS) biomarkers to explain the extrapulmonary effect of renal function decline due to subchronic inhalation exposure to particles smaller than 2.5 μm, as well as the correlation of the biomarkers with the particles' endotoxin content.
Materials And Methods: Adult male Sprague-Dawley rats were exposed to subchronic inhalation of particles smaller than 2.
Methods for Diagnosing Proteinuria: When to Use Which Test, and Why.
Am J Kidney Dis
December 2024
Medical Outpatient Department, University Hospital Basel, University Basel, Switzerland. Electronic address:
Proteinuria plays a central role in the diagnosis of kidney disease and has a high prognostic value. The test methods used differ considerably regarding impact on test accuracy, sensitivity, and specificity. Therefore, knowledge of the methodology is crucial for the interpretation of the results.
View Article and Find Full Text PDFAcute renal failure during treatment with Zoledronate in cancer patients.
J Oncol Pharm Pract
December 2024
Department of Medical Oncology, Habib Bourguiba Hospital University of Sfax, Sfax, Tunisia.
Background: Standard treatment for bone metastases is based on bisphosphonates such as zoledronic acid. The objective of this study was to evaluate the incidence of acute renal failure during treatment with Zoledronate and to analyze its correlated factors.
Materials And Methods: This is a retrospective study carried out at the medical oncology department of Habib Bourguiba University Hospital in Sfax, between January 2022 and March 2022.
Discordance between creatinine and cystatin C-based estimation of glomerular filtration rate (eGFR) in solid organ transplant recipients.
Clin Biochem
January 2025
Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, ON, Canada; Department of Clinical Biochemistry, Laboratory Medicine Program, University Health Network, Toronto, ON, Canada. Electronic address:
Background: Estimation of glomerular filtration rate is a critical component of assessing kidney function post-solid organ transplantation and in monitoring risk of acute injury. Our objective was to evaluate estimated glomerular filtration rate (eGFR) as derived from creatinine (eGFR), cystatin C (eGFR), and both (eGFR) in a cohort of transplant recipients.
Methods: A total of 47 unique post-solid organ transplant patients receiving tacrolimus were included.
Carbon dot-graphene oxide-based luminescent nanosensor for creatinine detection in human urine.
Mikrochim Acta
November 2024
Department of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh, India.
A fluorescence (FL)-based nanosensor has been devised for creatinine (CR) detection in human urine specimens. The proposed nanosensor utilized a nanocomposite (NC) of carbon dots (CDs) and graphene oxide (GO). The formation of CDs/GO NC reduced the CD FL emission (λ = 390 nm, λ = 461 nm) by ~ 75%.
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