Aim: To determine the association between self-reported adherence to anticholinergic medication and clinical outcomes in women with overactive bladder (OAB).
Methods: A prospective study of women with OAB treated with fesoterodine for 8 weeks. Adherence to medication was measured using the Medication Adherence Self-report Inventory (MASRI). A self reported adherence rate of ≥80% was considered adherent. The association between self-reported adherence and clinical outcomes (Global Index of Improvement, Global impression of Severity, urinary symptom and quality of life scores) was examined. We hypothesized that adherent women would have greater improvement in urinary symptoms and quality of life than non-adherent women.
Results: Based on the MASRI, 115 (62.5%) women were adherent and 69 (37.5%) were non-adherent to anticholinergic medication at 8weeks. Adherent women were more likely to report overall improvement in their symptoms compared to non-adherent women (84% vs. 24%, P < 0.001). Significantly more non-adherent women described their bladder symptoms as "moderate" or "severe" at 8 weeks compared to adherent women (74% vs. 44%, P = 0.03). At 8 weeks, adherent women reported significantly greater improvement (change) in urinary symptoms from baseline to 8 weeks than non-adherent women (-13.3 ± 25.8 vs. 2.5 ± 14.4, P = 0.04). Similarly, adherent women reported greater improvement in quality of life scores than non-adherent women (- 7.9 ± 24.0 vs. -1.8 ± 11.9, P = 0.003).
Conclusion: Self-reported non-adherence, as measured by the MASRI, is associated with clinically meaningful outcomes in women with OAB. This further validates the MASRI as a clinically useful tool for measuring adherence to anticholinergic medications in women with OAB. Neurourol. Urodynam. 35:738-742, 2016. © 2015 Wiley Periodicals, Inc.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654718 | PMC |
| http://dx.doi.org/10.1002/nau.22798 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Design and psychometric testing of a moral intelligence instrument for pre-hospital emergency medical services personnel: a sequential-exploratory mixed-method study.
BMC Emerg Med
January 2025
Department of Medical Surgical Nursing, School of Nursing, Fasa University of Medical Sciences, Fasa, 81936-13119, Iran.
Background: Moral intelligence is a significant and influential factor in the delivery of principled and high-quality care. This is because moral intelligence is the ability to recognize and be sensitive to moral issues, which contributes to the organization of appropriate behavior in the face of moral issues. This is particularly pertinent given that pre-hospital emergency medical services personnel (prehospital EMS personnel) frequently encounter stressful and tension-filled situations.
View Article and Find Full Text PDFDisrupted HIV care during COVID-19 pandemic associated with increased disabilities among people living with HIV in Belize.
Sci Rep
January 2025
Ph.D. Program in Global Health & Health Security, College of Public Health, Taipei Medical University, Taipei, Taiwan.
The COVID-19 pandemic may have impacted disabilities among people living with HIV; however, data on the association between COVID-19 pandemic-related healthcare disruptions and disabilities among people living with HIV is limited. We aimed to evaluate the association between COVID-19-affected HIV care behaviors and disability domains among people living with HIV in Belize. A cross-sectional study was conducted at the Western Regional Hospital and Southern Regional Hospital between August and October 2021 among people living with HIV in Belize aged ≥ 21 years and on antiretroviral therapy.
View Article and Find Full Text PDFWearable heart rate variability analysis system based on ionic conductive hydrogels.
Talanta
January 2025
Academy of Medical Engineering and Translational Medicine, Medical School, Tianjin University, Tianjin, 300072, China; School of Exercise and Health, Tianjin University of Sport, Tianjin, 300211, China. Electronic address:
Developing a wearable device that can continuously and reliably detect and evaluate heart rate variability (HRV) parameters is critical for the diabetic population with cardiac autonomic neuropathy (CAN). In this work, we proposed a zwitterionic conducting hydrogel that enabled a reliable and comfortable wearable device for the evaluation and detection of the autonomic nervous system (ANS). The hydrogel can achieve a strain of 2003 %, an electrical conductivity of 190 mS/m, and is capable of adhering to a variety of materials, including wood, plastic, and glass.
View Article and Find Full Text PDFOptimising Asthma Self-Management: Preliminary Validation of an Arabic Version of the Inhaler Technique Questionnaire.
Pharmacy (Basel)
January 2025
Pharmacy, School of Health and Biomedical Sciences, RMIT University, Melbourne, VIC 3083, Australia.
Background: Correct inhaler technique is vital for managing respiratory conditions like asthma. Patients from culturally and linguistically diverse backgrounds are at higher risk of sub-optimal adherence and errors in inhaler technique. This study aimed to validate an Arabic version of the inhaler technique questionnaire for self-assessment of the metered-dose inhaler (MDI) technique by assessing agreement between observed and self-reported techniques among Arabic-speaking individuals with asthma in Australia.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!