AI Article Synopsis
- - Fas is an important cell surface death receptor that plays a key role in regulating immune responses.
- - The study by Butt et al. (2015) reveals that Fas helps remove B cells that are not properly selected during immune development in the germinal center.
- - This process is crucial for maintaining a healthy immune system by ensuring only appropriately functioning B cells survive.
Article Abstract
Fas is a cell surface death receptor critical for immune regulation. In this issue of Immunity, Butt et al. (2015) show that Fas eliminates B cells that have become uncoupled from positive and negative selection in the germinal center.
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| http://dx.doi.org/10.1016/j.immuni.2015.05.005 | DOI Listing |
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