Therapeutic antibodies: Discovery, design and deployment.

Mol Immunol

Department of Antibody Engineering, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.

Published: October 2015

Therapeutic antibodies have come of age with major progress being made in cancer, autoimmunity and chronic inflammation, as well as a wide range of other human diseases. Antibody engineering is further driving development of novel antibody formats and genetically modified cell-based therapies that harness the power of the immune system to progress cures in otherwise intractable human diseases. Nevertheless, there are still significant challenges ahead for basic and applied research relating to therapeutic antibodies. This special issue of the journal provides reviews and opinions that relate to the discovery, design and deployment of antibodies as therapeutics.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molimm.2015.05.004DOI Listing

Publication Analysis

Top Keywords

therapeutic antibodies
12
discovery design
8
design deployment
8
human diseases
8
antibodies discovery
4
deployment therapeutic
4
antibodies age
4
age major
4
major progress
4
progress cancer
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!