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Pseudoachalasia is a disorder in which symptoms, radiologic, endoscopic, and manometric results resemble idiopathic achalasia. Although these diagnoses may appear similar, their underlying causes and therapy differ significantly. Pseudoachalasia is frequently associated with malignancy, particularly primary adenocarcinoma of the esophagus or cardia.

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Pseudoachalasia is a known complication following a gastric band placement that is reversible with band removal. However, the development of a sigmoid esophagus is uncommon. Sigmoid esophagus is considered late-stage achalasia and is associated with worse outcomes with myotomy compared to earlier-stage achalasia.

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Surgical Management of Persistent or New Symptoms After Hiatal Hernia Repair.

J Vis Exp

May 2024

Department of Surgery, MedStar Georgetown University Hospital; Department of Surgery, Division of Thoracic Surgery, MedStar Washington Hospital Center; Department of Surgery, Division of Thoracic Surgery, Sheikh Shakhbout Medical City;

Following a hiatal hernia repair, patients can present with recurrent or new symptoms. Symptoms can occur anywhere from weeks to years after surgery. These may include recurrent reflux, dysphagia, regurgitation, weight loss, or deteriorating quality of life.

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This case report describes the use of intravenous (IV) cangrelor as a transient tool for antiplatelet bridging therapy in a 70-year-old male with coronary artery disease and esophageal strictures who underwent recent percutaneous coronary intervention (PCI) and subsequently required a pre-oral endoscopic myomectomy (POEM) procedure. The patient was switched from oral clopidogrel to IV cangrelor drip prior to the procedure, which was successful in preventing stent thrombosis. The case highlights the potential benefits of IV antiplatelet therapy in patients unable to tolerate oral medications in the setting of esophageal obstructions following recent coronary stent placement in a critical care setting.

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Abnormal performance of peroral endoscopic myotomy (POEM): a case misdiagnosed as achalasia of cardia.

J Cardiothorac Surg

April 2024

Department of Thoracic Surgery, Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Shinan District, Qingdao, Shandong Province, China.

Background: Pseudoachalasia is a rare disease that behaves similarly to achalasia (AC), making it sometimes difficult to differentiate.

Case Presentation: We report a case of 49-year-old male with adenocarcinoma of the gastroesophageal junction misdiagnosed as achalasia. No obvious abnormalities were found in his initial examinations including upper digestive endoscopy, upper gastrointestinal imaging and chest computed tomography (CT).

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