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Ranolazine can markedly increase tacrolimus blood levels. | LitMetric
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Ranolazine can markedly increase tacrolimus blood levels.

Sidy Seck Marianna Bellantoni Carmine Zoccali Giuseppe Enia

NDT Plus

Nephrology, Hypertension and Renal Transplantation Unit, CNR-IBIM Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension, Ospedali Riuniti , Reggio Calabria, Italy.

Published: February 2011

We report the case of a renal transplant patient on tacrolimus who developed a fully reversible renal failure and a doubling in serum tacrolimus closely associated with initiation of ranolazine (Ranexa) treatment, a new anti-angina drug recently introduced in Europe.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421639PMC
http://dx.doi.org/10.1093/ndtplus/sfq180DOI Listing

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