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IgA nephropathy in a patient presenting with scleritis. | LitMetric

AI Article Synopsis

  • Scleritis is rare in IgA nephropathy patients, and this case involved a patient with diffuse anterior scleritis along with signs of kidney issues like microscopic hematuria and nephrotic range proteinuria.
  • Laboratory tests ruled out several conditions, including lupus and various infections, and a renal biopsy confirmed IgA nephropathy.
  • After starting oral steroids, the patient became asymptomatic, with no recurrence of scleritis, normal ophthalmological exams, and stable renal function, although proteinuria remained at a non-nephrotic level.

Article Abstract

Scleritis is a very uncommon manifestation in patients with IgA nephropathy. Here, we report the case of a patient presenting with diffuse anterior scleritis in which the laboratory disclosed microscopic haematuria and nephrotic range proteinuria. Renal function was normal. Serology for lupus, vasculitis and cryoglobulinaemia was negative. Rheumatoid factor was negative, and serum C3 and serum C4 were on the normal range. Serology for human immunodeficiency virus types 1 and 2, hepatitis B, hepatitis C, syphilis, and Lyme disease was also negative. A renal biopsy was performed and revealed IgA nephropathy. Oral steroids were then started, and 6 months later, the patient was asymptomatic. Scleritis did not recur, and ophthalmologic examination was normal; however, proteinuria was still in non-nephrotic range. Renal function still remains normal.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421692PMC
http://dx.doi.org/10.1093/ndtplus/sfq103DOI Listing

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