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Research on injection molded parts defect detection algorithm based on multiplicative feature fusion and improved attention mechanism.
Sci Rep
December 2024
School of Construction Machinery, Shandong Jiaotong University, Jinan, 250023, China.
Injection molded parts are increasingly utilized across various industries due to their cost-effectiveness, lightweight nature, and durability. However, traditional defect detection methods for these parts often rely on manual visual inspection, which is inefficient, expensive, and prone to errors. To enhance the accuracy of defect detection in injection molded parts, a new method called MRB-YOLO, based on the YOLOv8 model, has been proposed.
View Article and Find Full Text PDFConstructing High-Yielding for (-)-α-Bisabolol Production Based on the Exogenous Haloarchaeal MVA Pathway and Endogenous Molecular Chaperones.
J Agric Food Chem
December 2024
The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu 214122, China.
(-)-α-Bisabolol exhibits analgesic, anti-inflammatory, and skin-soothing properties and is widely applied in the cosmetic and pharmaceutical industries. The use of plant essential oil distillation or chemical synthesis to produce (-)-α-bisabolol is both inefficient and unsustainable. Currently, the microbial production of (-)-α-bisabolol mainly relies on and as chassis strains; however, high concentrations of (-)-α-bisabolol have certain toxicity to the strain.
View Article and Find Full Text PDFHigh-throughput optimisation of protein secretion in yeast via an engineered biosensor.
Trends Biotechnol
December 2024
Research School of Biology, Australian National University, Canberra, ACT 2600, Australia. Electronic address:
Secretion of high-value proteins and enzymes is fundamental to the synthetic biology economy, allowing continuous fermentation during production and protein purification without cell lysis. Most eukaryotic protein secretion is encoded by an N-terminal signal peptide (SP); however, the strong impact of SP sequence variation on the secretion efficiency of a given protein is not well defined. Despite high natural SP sequence diversity, most recombinant protein secretion systems use only a few well-characterised SPs.
View Article and Find Full Text PDFInduction and Characteristics of Callus Cultures of the Medicinal Plant L.
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Department of Plant Physiology and Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University in Kraków, Gronostajowa 7, 30-387 Kraków, Poland.
L. is a traditional medicinal plant valued for its potentially health-promoting metabolites. Its herbal raw material has been recognized and used since ancient times and continues to be widely used in traditional medicine.
View Article and Find Full Text PDFThe cell cycle inhibitor p21 is essential for irinotecan-induced senescence and plays a decisive role in re-sensitization of temozolomide-resistant glioblastoma cells to irinotecan.
Biomed Pharmacother
December 2024
Department of Toxicology, University Medical Center of the Johannes Gutenberg University, Obere Zahlbacher Str. 67, Mainz D-55131, Germany. Electronic address:
Background And Purpose: Standard of care for glioblastomas includes radio-chemotherapy with the monoalkylating compound temozolomide. Temozolomide induces primarily senescence, inefficiently killing glioblastoma cells. Recurrences are inevitable.
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