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Platelet signaling in immune landscape: comprehensive mechanism and clinical therapy.
Biomark Res
December 2024
Institute of Clinical Pharmacology, Peking University First Hospital, Beijing, China.
Platelets are essential for blood clotting and maintaining normal hemostasis. In pathological conditions, platelets are increasingly recognized as crucial regulatory factors in various immune-mediated inflammatory diseases. Resting platelets are induced by various factors such as immune complexes through Fc receptors, platelet-targeting autoantibodies and other platelet-activating stimuli.
View Article and Find Full Text PDFTHE EFFECTIVENESS OF PLATELET RICH FIBRIN IN ALVEOLAR RIDGE RECONSTRUCTIVE OR GUIDED BONE REGENERATIVE PROCEDURES: A SYSTEMATIC REVIEW AND META-ANALYSIS.: platelet rich fibrin in alveolar ridge augmentation.
J Dent
December 2024
Periodontology Unit, Centre for Host Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King's College London, London, United Kingdom. Electronic address:
Introduction And Objectives: Clinical studies have shown favorable outcomes following use of platelet rich fibrin (PRF), either alone or in conjunction with biomaterials for alveolar ridge reconstruction (ARR) or guided bone regeneration (GBR) . While PRF application accelerates wound healing and reduces postoperative discomfort, its effects on the alveolar bone gain, as part of ARR or GBR is less clear. Therefore, this study aims to investigate the clinical effectiveness of PRF when used in ARR or GBR, as well as postoperative discomfort following these procedures.
View Article and Find Full Text PDFDrug-Drug Interactions Between DAAs and Anticoagulants or Antiplatelets: A Position Paper of the Italian Anticoagulation Clinics.
Liver Int
February 2025
Emergency Medicine and Thrombosis and Haemostasis Center, ASST Sette Laghi, Varese, Italy.
The natural history of chronic hepatitis C virus (HCV) infection has changed after the introduction of direct-acting antiviral agents (DAAs). Screening programs have been ongoing to reach the World Health Organisation's goal of HCV elimination by 2030, and most infected people are eligible for treatment. Given the increased cardiovascular risk in people with HCV infection and the metabolic pathways of DAAs, it is not uncommon to face the issue of drug-drug interactions (DDIs) with antiplatelet or anticoagulant drugs.
View Article and Find Full Text PDFAssociation between serum hypertriglyceridemia and hematological indices: data mining approaches.
BMC Med Inform Decis Mak
December 2024
Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Background: High triglyceride (TG) affects and is affected of other hematological factors. The determination of serum fasted triglycerides concentrations, as part of a lipid profile, is crucial key point in hematological factors and significantly affect various systemic diseases. This study was carried out to assess the potential relation between the concentration of TG and hematological factors.
View Article and Find Full Text PDFImpact of Bambusa vulgaris-supplemented diet on Nile tilapia challenged with Pseudomonas putida: Hematological, immune, and oxidative responses.
Fish Shellfish Immunol
December 2024
Department of Microbiology and Immunology, Faculty of Veterinary Medicine, Assiut University, Assiut, 71526, Egypt.
This study investigated the effects of bamboo shoot extract (Bambusa vulgaris) as a feed additive on the health profiles and infection resistance of Nile tilapia (Oreochromis niloticus) against Pseudomonas putida. Bamboo shoot extract was added at levels of 0 g, 40 g, and 60 g per 1000 g of diet over a 60-day period. The fish were then challenged with a pathogenic P.
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