Background: This investigation was aimed at assessing the clinical significance of microalbuminuria (MA) in predicting in-hospital adverse outcomes amongst the patients with coronary artery disease (CAD) and type 2 diabetes mellitus (DM) who have undergone coronary artery bypass graft (CABG) surgery.
Methods: We recruited 720 consecutive Caucasian (Russian) patients who underwent CABG surgery during 2011-2012.
Results: Patients with renal dysfunction (RD) and without type 2 DM had significantly higher median serum creatinine seven days after CABG surgery compared to patients without RD and type 2 DM. There were no statistically significant intergroup differences regarding glomerular filtration rate. However, the highest median of urine albumin excretion 24hours before and seven days after CABG surgery was detected in patients with RD and type 2 DM whilst the lowest median was noted in patients without RD and type 2 DM. Median of urine albumin excretion 24hours before and seven days after CABG surgery in patients with adverse outcome was significantly higher compared to patients with a favourable outcome.
Conclusions: We suggest that the determination of MA before and after CABG surgery may assist in predicting adverse outcomes after CABG surgery.
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http://dx.doi.org/10.1016/j.hlc.2015.03.004 | DOI Listing |
Cardiovasc Drugs Ther
January 2025
Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, The Department of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangzhou, Guangdong Province, China.
Purpose: Coronary endarterectomy combined with coronary artery bypass grafting (CE-CABG) effectively achieves coronary revascularization in patients with diffuse atherosclerotic coronary artery disease (CAD). However, the loss of the subendothelial tissue at the CE-CABG coronary artery accelerates local thrombosis, leading to CE-CABG graft failure. Dual antiplatelet therapy (DAT) and warfarin plus aspirin (WPA) are the two most common anticoagulation strategies post CE-CABG.
View Article and Find Full Text PDFSci Rep
January 2025
Tehran Heart Center, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Chronic obstructive pulmonary disease (COPD) is a common condition that complicates major surgeries like coronary artery bypass grafting (CABG). This study aims to evaluate the impact of COPD on the outcome of CABG. A registry-based retrospective cohort study included individuals who received CABG between 2009 and 2016.
View Article and Find Full Text PDFAnn Thorac Surg
January 2025
Department of Cardiac Surgery, Ippokrateio General Hospital of Athens, Athens, Greece.
J Am Coll Surg
January 2025
Department of Surgery, The Ohio State University Wexner Medical Center and James Comprehensive Cancer Center, Columbus, OH.
Introduction: We aimed to investigate the geographic variation of Academic Medical Centers (AMCs) across different healthcare markets and the impact on surgical outcomes in nearby non-AMCs.
Methods: Patients who underwent major surgery between 2016 and 2021 were identified from the Medicare Standard Analytic Files. Healthcare markets were delineated using Dartmouth Atlas hospital referral regions.
Cureus
December 2024
Department of Cardiothoracic Surgery, HonorHealth, Scottsdale, USA.
Background Cardiac surgery-associated acute kidney injury (CSA-AKI) remains a significant complication following coronary artery bypass grafting (CABG), affecting 22%-30% of patients. This study evaluates the efficacy of NephroCheck, a biomarker-based test measuring insulin-like growth factor-binding protein 7 (IGFBP7) and tissue inhibitor of metalloproteinases-2 (TIMP2), in predicting postoperative AKI. Methods In this retrospective observational cohort study, 21 patients undergoing isolated CABG were analyzed.
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