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Nocturia as a clinical marker of loss of function and resilience or risk factor for frailty in older adults? Results of the Berlin Aging Study II.
Geroscience
January 2025
Medical Department of Endocrinology and Metabolic Diseaseas (including Lipid Metabolism), Charité-Universitätsmedizin Berlin, Berlin, Germany.
The current study examined cross-sectional and longitudinal associations between nocturia and frailty in a cohort of men and women aged 60 years and older, as evidence on this topic was lacking. We analyzed baseline and follow-up data (n = 1671) from the Berlin Aging Study II (BASE-II), a prospective longitudinal cohort study focusing on the factors associated with "healthy" vs. "unhealthy" aging.
View Article and Find Full Text PDFCombination of Metabolomics and Bioinformatics to Reveal the Mechanism of Luteolin in the Treatment of Cervical Cancer.
Chem Biol Drug Des
February 2025
Department of Acupuncture, Shenzhen Traditional Chinese Medicine Hospital, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, China.
The incidence of cervical cancer is high among women globally. The potential therapeutic efficacy of luteolin in the treatment of cervical cancer has been identified. Therefore, we aim to elucidate the mechanism of action of luteolin in the treatment of cervical cancer through a comprehensive approach that integrates metabolomics with bioinformatics.
View Article and Find Full Text PDFMonitoring and assessment of population, reproductive, and health effects in colonial waterbirds breeding at contaminated Great Lakes sites in Michigan.
Environ Toxicol Chem
January 2025
U.S. Fish and Wildlife Service, Michigan Ecological Services Field Office, East Lansing, MI, United States.
Immunological, reproductive, and population endpoints were assessed in fish-eating birds during 2010-2019 in the Saginaw River and Bay and River Raisin Areas of Concern (AOCs) and Grand Traverse Bay, which are ecosystems historically contaminated with polychlorinated biphenyls, dibenzo-p-dioxins, and dibenzofurans. Reference sites were in the lower St. Marys River (herring gulls and Caspian terns), eastern Lake Superior (terns), and eastern Lake Huron (black-crowned night herons).
View Article and Find Full Text PDFQuantifying the potential value of entomological data collection for programmatic decision-making on malaria control in sub-Saharan African settings.
Malar J
January 2025
MRC Centre for Global Infectious Disease Analysis, Imperial College London, London, UK.
Background: The availability of many tools for malaria control leads to complex decisions regarding the most cost-effective intervention package based on local epidemiology. Mosquito characteristics influence the impact of vector control, but entomological surveillance is often limited due to a lack of resources in national malaria programmes.
Methods: This study quantified the monetary value of information provided by entomological data collection for programmatic decision-making using a mathematical model of Plasmodium falciparum transmission.
Biofabrication of zinc oxide nanoparticles using Moringa oleifera, characterization and statistical optimization for their application in crystal violet adsorption.
Sci Rep
January 2025
Department of Biology, College of Sciences and Arts Khulais, University of Jeddah, 21959, Jeddah, Saudi Arabia.
Crystal violet (Cry) is an essential textile dye belonging to the triphenylmethane group, that is widely used in the textile industry. It is also applied for paper printing and Gram staining. Previously, it was significant as a topical antiseptic due to its antibacterial, antifungal, and anthelmintic properties.
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