For the high cost and mobility issues, a home uterine contraction pressure monitoring system based on Windows CE platform was developed. In this paper, the design of hardware circuit, micro-controller system and LabVIEW program based on Windows CE are discussed. The clinical validation experiment in hospital for this system was made and the experimental results show that this system complies with the trend that current medical equipment is becoming portable, homely and networked. Through real-time monitoring uterine contraction pressure, occurrence of premature birth and abortion can be prevented effectively.
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J Neurosci
January 2025
Department of Biology, University of Miami, Coral Gables, FL 33143 USA
Neuroendocrine cells react to physical, chemical, and synaptic signals originating from tissues and the nervous system, releasing hormones that regulate various body functions beyond the synapse. Neuroendocrine cells are often embedded in complex tissues making direct tests of their activation mechanisms and signaling effects difficult to study. In the nematode worm , four uterine-vulval (uv1) neuroendocrine cells sit above the vulval canal next to the egg-laying circuit, releasing tyramine and neuropeptides that feedback to inhibit egg laying.
View Article and Find Full Text PDFAm J Obstet Gynecol MFM
January 2025
Department of Anaesthesiology and Critical Care, Jawaharlal Institute of Post Graduate Medical Education and Research, Puducherry, India. Electronic address:
Background: Preclinical studies have documented the role of alpha-adrenergic agonists in myometrial contraction. Phenylephrine is frequently used to prevent and treat post-spinal hypotension during cesarean delivery. We hypothesized phenylephrine would reduce postpartum blood loss due to alpha-1 receptor-mediated uterine and vascular smooth muscle contraction.
View Article and Find Full Text PDFReprod Sci
January 2025
Department of Pharmacology, University of Nevada, Reno School of Medicine, 1664 North Virginia St., Reno, NV, 89557, USA.
Matrix metallopeptidase 9 (MMP9) is a secreted zinc-dependent peptidase known for extracellular remodeling. MMP9 is elevated in tissues from women experiencing preterm labor, and previous research has shown that the addition of combined matrix metallopeptidases 2 and 9 (MMP2/9) enhances uterine contractions. We hypothesized that adding MMP9 alone would enhance myometrial contractions and that specific MMP9 inhibition would suppress uterine contractions.
View Article and Find Full Text PDFArch Gynecol Obstet
January 2025
Department of Perinatal Maternal and Child Medical Center, Shizuoka Children's Hospital, 860 Urushiyama, Aoi-Ku, Shizuoka-Shi, Shizuoka, 420-8660, Japan.
Purpose: This study aimed to investigate the usefulness of emergency cerclage for pregnant women with bulging fetal membranes, as indicated by our original noninvasive clinical scoring system.
Methods: This was a retrospective study of pregnant women who underwent emergency cerclage for bulging fetal membranes within 28 weeks. The primary outcome was the continuation of pregnancy at 34 gestational weeks in singleton pregnancies and 32 gestational weeks in twin pregnancies.
Placenta
December 2024
Department of Obstetrics and Gynecology, Máxima MC, P.O. Box 7777, 5500 MB, Veldhoven, the Netherlands; Department of Electrical Engineering, Eindhoven University of Technology, P.O. Box 513, 5600 MB, Eindhoven, the Netherlands; Eindhoven MedTech Innovation Center (e/MTIC), P.O. Box 513, 5600 MB, Eindhoven, the Netherlands.
Introduction: The postpartum period can be complicated by hemorrhage, frequently caused by uterine atony. Electrohysterography, allowing continuous monitoring of uterine activity, may be a promising alternative for early detection of uterine atony, and thereby contribute to the prevention of postpartum hemorrhage. Associations between electrohysterographic parameters postpartum and total blood loss were studied.
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