During colitis, gut bacteria and bacterial components can traverse the mucus layer and contact host cells. In this issue of Cell Host & Microbe, Hickey et al. (2015) show that sulfatases of Bacteroides thetaiotaomicron are required for its outer membrane vesicles to transit to underlying host immune cells and cause colitis.
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| http://dx.doi.org/10.1016/j.chom.2015.04.012 | DOI Listing |
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