AI Article Synopsis

  • Thyroid nodules are common issues, and fine-needle biopsy (FNB) is the usual method for assessing them; this study compares aspiration versus nonaspiration techniques.
  • A study involving 309 patients analyzed the quality of tissue samples from both biopsy methods, with smears evaluated by a pathologist using a specific scoring system.
  • The findings revealed no significant difference in the quality of samples from either technique, suggesting both are valid screening methods for checking thyroid nodules.

Article Abstract

Unlabelled: Thyroid nodules are a common pathology of the thyroid gland. Thyroid fine-needle biopsy (FNB) is a technique used as the first step in the assessment of thyroid nodules. Some au- thors have demonstrated the superiority of nonaspiration compared with aspiration biopsy.

Aim: The objective was to assess whether there are significant differences between the two thyroid biopsy techniques.

Material And Methods: The study group comprised 309 patients with thyroid nodules admitted to the Endocrinology Clinic of the Iasi "St. Spiridon "Hospital between 2005 and 2008 in which fine-needle nonaspiration or aspiration biopsy was performed. The slides were read by one pathologist. The smears were stained using the May-Grunwald-Giemsa method (MGG). The quality of smears obtained by the two sampling techniques was evaluated by using the scoring system developed by Mair.

Results And Discussion: No differences in smear quality between the two sampling techniques in terms of blood contamination, amount of cellular material, degree of cellular degeneration, degree of cellular trauma, and preservation of appropriate architecture were found.

Conclusion: The results of this study show that the sensitivity and specificity of both techniques allow their use as standard screening methods for thyroid nodular lesions.

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