Rhabdomyoma is a rare tumor of skeletal muscle origin which can occur in different localizations. The head and neck region is a site of predilection for the adult type. Its absolutely benign behavior makes correct diagnosis crucial. In this study, a case of an extracardiac rhabdomyoma of the larynx was found to recur 12 years after initial treatment. Following its surgical removal, histology showed typical patterns of an adult type of rhabdomyoma with focal cross-striations. Immunocytochemically, all applied muscular markers were positive. Electron microscopy revealed muscular filaments with cross-striations and glycogen granules. These findings showed that immunocytochemistry plays an important role in differential diagnosis and the need for possible further treatment.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/BF00453667 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Fetal Rhabdomyoma of the Larynx in an Adult.
Ear Nose Throat J
April 2024
Department of Molecular Medicine, Sapienza University, Rome, Italy.
Approach to small biopsies in the larynx.
Semin Diagn Pathol
September 2023
Department of Pathology, E422 Doan Hall, 410W 10th Ave, Columbus, OH 43210, United States. Electronic address:
Small biopsies in the larynx can make a definitive diagnosis challenging due to the sampling or tangential sectioning. The differential diagnosis can be divided into mucosal lesions (squamous papillomas, intraepithelial dysplasia, and invasive squamous cell carcinoma) or submucosal lesions (vocal cord polyps/nodules, amyloidosis, granular cell tumor, rhabdomyoma, neuroendocrine neoplasms, salivary gland tumors, and cartilaginous tumors). Diagnostic criteria (both morphologic and immunohistochemical) are reviewed to arrive at a diagnosis even on small biopsy.
View Article and Find Full Text PDFTop Ten Oncocytic Head and Neck Lesions to Contemplate.
Head Neck Pathol
March 2023
Department of Pathology, Duke University, Durham, NC, USA.
Background: Oncocytes are a component of many metaplastic and neoplastic lesions throughout the head and neck area, primarily originating in salivary/seromucinous glands and the thyroid gland. In addition, other lesions can contain cells that mimic oncocytes (pseudo-oncocytes); these can be of epithelial or non-epithelial origin.
Methods: Review article.
Histopathological Study of Benign Tumours of the Larynx: A Descriptive Study in Coastal Karnataka.
Indian J Otolaryngol Head Neck Surg
October 2022
Department of Otorhinolaryngology, Kasturba Medical College, Mangalore (Manipal Academy of Higher Education), Hampankatta, Mangalore, 575001 India.
A laryngoscopically benign lesion with minimal hoarseness may turn out to be mimickers of malignancy or malignancy itself. Histopathological study is mandatory in such cases to rule out malignancy. A descriptive study of histopathological and laryngoscopic findings of benign laryngeal lesions were studies over a period of 4.
View Article and Find Full Text PDFRhabdomyoma of the Larynx: A Case Report and Literature Review of a Rare Tumor in an Uncommon Location.
J Voice
January 2025
Baylor, Scott and White The Voice Center, Baylor University Medical Center, Dallas, Texas, USA.
Objectives: Laryngeal rhabdomyomas are extremely rare, benign striated muscle tumors that have been documented only ∼50 times in the literature. They can be subdivided into two types: fetal and adult types, with the adult type being more common. Common presenting symptoms include hoarseness or progressive dysphagia.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!