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| http://dx.doi.org/10.1159/000430801 | DOI Listing |
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Neck circumference as a potential indicator of pre-sarcopenic obesity in a cohort of community-based individuals.
Clin Nutr
January 2024
Department of Endocrinology and Metabolism, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai 200233, China. Electronic address:
Background & Aims: ESPEN/EASO advocates screening for sarcopenic obesity based on the concomitant presence of an elevated body mass index (BMI) or waist circumference. Neck circumference (NC) is another simple and reliable anthropometric measurement for estimating obesity; however, its ability to detect sarcopenic obesity has not yet been established. The aim of the present study was to explore the association between NC and sarcopenic obesity in a Shanghai community population.
View Article and Find Full Text PDFA comprehensive descriptive assessment of obesity related chronic morbidity and estimated annual cost burden from a population-based electronic health record database.
Isr J Health Policy Res
June 2020
Clalit Research Institute, Clalit Health Services, 2 Shoham, 5251003, Ramat Gan, Israel.
Background: The growing prevalence of obesity and its complications pose a huge burden on the individual and health care systems worldwide. This study presents the frequency of multiple prevalent co-morbidities and estimated annual cost burden by body mass index (BMI) groups, age, and sex among the Israeli adult population to provide policy makers with further evidence to appropriately target interventions.
Methods: This cross-sectional study utilized population-based electronic medical records from the largest payer-provider health fund in Israel.
Midazolam Pharmacokinetics in Obese and Non-obese Children and Adolescents.
Clin Pharmacokinet
May 2020
Department of Clinical Pharmacology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Bispebjerg Bakke, Entrance 20C, 2nd floor, 2400, Copenhagen, Denmark.
Background: Midazolam is a first-line drug for the treatment of status epilepticus, both by buccal and intravenous administration. In children and adolescents with obesity, midazolam pharmacokinetics may be altered, and the current dosing guidelines may therefore be insufficient.
Objective: The objective of this study was to investigate the pharmacokinetics of midazolam, after intravenous administration, in obese and non-obese adolescents aged 11-18 years.
All-Cause Mortality Following Bariatric Surgery in Smokers and Non-smokers.
Obes Surg
December 2019
Clalit Research Institute, Chief Physician's Office, Clalit Health Services, Tel Aviv, Israel.
Introduction: Bariatric surgery is associated with lower all-cause mortality, but many studies exclude smokers. We sought to determine if the association of mortality and bariatric surgery differs between smokers and non-smokers.
Materials And Methods: We conducted a retrospective cohort study in a large Israeli integrated payer/provider health care organization.
Association of Bariatric Surgery Using Laparoscopic Banding, Roux-en-Y Gastric Bypass, or Laparoscopic Sleeve Gastrectomy vs Usual Care Obesity Management With All-Cause Mortality.
JAMA
January 2018
Clalit Research Institute, Clalit Health Services, Tel Aviv, Israel.
Importance: Bariatric surgery is an effective and safe approach for weight loss and short-term improvement in metabolic disorders such as diabetes. However, studies have been limited in most settings by lack of a nonsurgical group, losses to follow-up, missing data, and small sample sizes in clinical trials and observational studies.
Objective: To assess the association of 3 common types of bariatric surgery compared with nonsurgical treatment with mortality and other clinical outcomes among obese patients.
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