Glycation and its products cause a host of pathological conditions but their exact roles are yet to be determined. Pyrraline, a key product of glycation, and a novel pyrraline-derived cross-link have been incorporated into collagenous peptides via Maillard condensations performed on resin-bound peptide sequences.
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http://dx.doi.org/10.1039/c5cc03052h | DOI Listing |
Int J Biol Macromol
January 2025
Key Laboratory of Automobile Materials, Ministry of Education, and College of Materials Science and Engineering, Jilin University, Changchun 130025, China. Electronic address:
A new type of filler was added to epoxy resin to prepare a composite coating with excellent corrosion and weathering resistance. The simple synthesis process and nonpolluting raw materials of this filler contribute to the development of green chemistry. Specifically, lignin was encapsulated in mesoporous silica, the synergistic effect between the two resulted in the formation of lignin/mesoporous silica composite particles (MSN-L) with excellent ultraviolet (UV) resistance.
View Article and Find Full Text PDFMolecules
January 2025
Department of Chemistry, Ball State University, Muncie, IN 47306, USA.
Ipomoeassin F (Ipom-F) is a plant-derived macrocyclic resin glycoside that potently inhibits cancer cell growth through blockage of Sec61-mediated protein translocation at the endoplasmic reticulum. Recently, detailed structural information on how Ipom-F binds to Sec61α was obtained using Cryo-EM, which discovered that polar interactions between asparagine-300 (N300) in Sec61α and four oxygens in Ipom-F are crucial. One of the four oxygens is from the carbonyl group at C-4 of the fatty acid chain.
View Article and Find Full Text PDFInt J Mol Sci
January 2025
School of Materials Science and Engineering, PCFM Lab, GD HPPC Lab, Sun Yat-sen University, Guangzhou 510275, China.
As a kind of high-performance thermoplastic crystalline resin, poly(4-methyl-1-pentene) (PMP) is characterized by its low density, low dielectric constant, exceptional mechanical and chemical properties, high transparency, and gas permeability. PMP has recently received more attention since COVID-19, because it is used as a hollow-fiber membrane for extracorporeal membrane oxygenation (ECMO) based on its high permeability and excellent biocompatibility. This review summarizes the chemical structure, synthesis, properties, and application of PMP.
View Article and Find Full Text PDFClin Oral Investig
January 2025
Department of Restorative Dentistry - Endodontics, Faculdade de Odontologia de Piracicaba, Universidade Estadual de Campinas, Piracicaba, SP, Brazil.
Objectives: To investigate volumetric changes, in vivo biocompatibility, and systemic migration from eight commercial endodontic sealer materials in paste/paste, powder/liquid, and pre-mixed forms.
Materials And Methods: The sealers AH Plus Bioceramic, AH Plus Jet, BioRoot RCS, MTApex, Bio-C Sealer, Bio-C Sealer Ion+, EndoSequence BC Sealer and NeoSEALER Flo were studied. After characterisation by scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDS), Raman spectroscopy and X-ray diffractometry (XRD), tubes were implanted in Wistar rats' alveolar bone and subcutaneous tissues.
Mol Cell Endocrinol
January 2025
Programa de Pós-graduação em Medicina (Endocrinologia), Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro-RJ, Brazil; Centro de Pesquisa em Medicina de Precisão, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro-RJ, Brazil; Programa de Pós-graduação em Ciências Biológicas (Fisiologia), Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro-RJ, Brazil.
The large-scale industrial production characteristic of the last century led to an increase in man-made compounds and mobilization of natural compounds, many of which can accumulate in the environment and organisms due to their bioaccumulation and biomagnification properties. The endocrine system is especially vulnerable to these compounds that are known as endocrine disruptor chemicals (EDCs). Thyroid hormones (THs) are essential for normal development and growth, besides being the main regulators of basal metabolic rate.
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