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Global retention model based on multisample system parameters for optimising chromatographic fingerprints of medicinal plants.
Anal Chim Acta
February 2025
Department of Analytical Chemistry, Faculty of Chemistry, Universitat de València, C/ Dr. Moliner 50, 46100, Burjassot, Spain. Electronic address:
Background: Developing analytical methods for Traditional Medicine products by liquid chromatography is challenging due to their chemical complexity and the lack of analytical standards for numerous, unidentified constituents. Regulatory agencies recommend chromatographic fingerprint analysis for quality evaluation, relying on peak detection to ensure resolution. Conventional modelling struggles to optimise experimental conditions for such complex samples.
View Article and Find Full Text PDFAnalysis of volatile compounds and vintage discrimination of raw Pu-erh tea based on GC-IMS and GC-MS combined with data fusion.
J Chromatogr A
January 2025
College of Light Industry and Food Engineering, Nanjing Forestry University, Longpan Road 159, Nanjing 210037, China. Electronic address:
Storage duration significantly influences the aroma profile of raw Pu-erh tea. To comprehensively investigate the differences in the volatile compounds across various vintages of raw Pu-erh teas and achieve the rapid classification of tea vintages, volatile compounds of raw Pu-erh tea with different years (2020-2023) were analyzed using a combination of gas chromatography-ion mobility spectrometry (GC-IMS) and gas chromatography-mass spectrometry (GC-MS). The datasets obtained from both techniques were integrated through low-level and mid-level data fusion strategies.
View Article and Find Full Text PDFEpigallocatechin 3-gallate-induced neuroprotection in neurodegenerative diseases: molecular mechanisms and clinical insights.
Mol Cell Biochem
January 2025
Department of Biomedical, Surgical and Dental Sciences, University of Milan, Via Luigi Vanvitelli 32, 20133, Milan, Italy.
Neurodegenerative diseases (NDs) are caused by progressive neuronal death and cognitive decline. Epigallocatechin 3-gallate (EGCG) is a polyphenolic molecule in green tea as a neuroprotective agent. This review evaluates the therapeutic effects of EGCG and explores the molecular mechanisms that show its neuroprotective properties.
View Article and Find Full Text PDFAssociations of Tea Consumption With the Risk of All-Cause and Cause-Specific Mortality Among Adults With Type 2 Diabetes: A Prospective Cohort Study in China.
J Diabetes
January 2025
Department of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing, China.
Aims: To investigate the associations of tea consumption with all-cause and cause-specific mortality among type 2 diabetes mellitus (T2DM) Chinese patients.
Materials And Methods: The present study included 15 718 participants from the Comprehensive Research on the Prevention and Control of Diabetes between 2013 and 2014 in Jiangsu, China. Information on tea consumption (including frequency, amount, and duration) was collected at baseline using interviewer-administered questionnaires.
A highly sensitive photoelectrochemical sensor for the detection of theophylline based on the photoelectrocatalytic activity of a nanocomposite of polydopamine nanospheres and gold nanoparticles.
Anal Methods
January 2025
School of Pharmacy, Wannan Medical College, Wuhu 241002, China.
A label-free photoelectrochemical (PEC) sensor for detecting theophylline (TP) was exploited based on electrodes modified with a nanocomposite of polydopamine nanospheres (PDSs) and gold nanoparticles (AuNPs). PDS particles were prepared by oxidative autopolymerization, and their reducibility was utilized in one step to reduce the gold nanoparticles . The AuNPs-PDS/ZnS PEC sensor was constructed by electrochemical deposition and drop coating.
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