Mic10 Oligomerization Pinches off Mitochondrial Cristae.

Cell Metab

Max Planck Institute for Biology of Ageing, Joseph-Stelzmann-Strasse 9b, 50931 Cologne, Germany. Electronic address:

Published: May 2015

The mitochondrial contact site and cristae organizing system (MICOS) complex is essential for normal mitochondria biogenesis and morphology. In this issue, Bohnert et al. (2015) and Barbot et al. (2015) demonstrate that a MICOS core subunit, Mic10, is crucial for mitochondrial cristae formation by forming oligomers at the cristae junctions.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431669PMC
http://dx.doi.org/10.1016/j.cmet.2015.04.020DOI Listing

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