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Clinical outcomes of peroral endoscopic myotomy with and without septotomy for management of epiphrenic diverticula: an international multicenter experience (with video).
Gastrointest Endosc
November 2024
Division of Gastroenterology and Hepatology, Johns Hopkins Hospital, Baltimore, Maryland, USA. Electronic address:
Article Synopsis
- This study aimed to evaluate the effectiveness and safety of two procedures—peroral endoscopic myotomy with septotomy (POEM+S) and without septotomy (POEM-S)—in treating symptomatic epiphrenic diverticula (ED) alongside motility disorders.
- Conducted across 21 international centers from 2014 to 2023, the study included 85 patients, measuring clinical success primarily through the Eckardt score.
- Results indicated that both procedures had similar clinical success rates (83% for POEM+S vs. 86.8% for POEM-S), technical success, and adverse event rates, but POEM-S patients had a longer hospital stay.
Nasopharyngeal airway assistance improves esophageal intubation rates of high-resolution esophageal manometry catheters.
Neurogastroenterol Motil
August 2024
Division of Gastroenterology & Hepatology, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Background: High-resolution esophageal manometry (HREM) is the gold standard test for esophageal motility disorders. Nasopharyngeal airway-assisted insertion of the HREM catheter is a suggested salvage technique for failure from the inability to pass the catheter through the upper esophageal sphincter (UES). It has not been demonstrated that the nasopharyngeal airway improves procedural success rate.
View Article and Find Full Text PDFSymptomatic Epiphrenic Diverticulum in an Older Patient Successfully Treated Nonsurgically.
Intern Med
September 2024
Department of Gastroenterology, Toranomon Hospital, Japan.
Epiphrenic diverticulum is a rare condition commonly diagnosed in middle-aged adults. Symptoms include dysphagia and regurgitation, which are associated with underlying esophageal motility disorders. We herein report a 93-year-old woman with dysphagia diagnosed with symptomatic epiphrenic diverticulum by computed tomography, esophagogastroduodenoscopy, and esophagography.
View Article and Find Full Text PDFCharacteristics of Esophageal Motility and Associated Symptom Profiles in Patients with Esophageal Diverticulum: A Study Based on High-Resolution Impedance Manometry.
Dig Dis Sci
February 2024
Department of Internal Medicine, National Taiwan University Hospital, No.7, Chung-Shan South Road, Taipei, Taiwan.
Background: Esophageal diverticulum (ED) is an uncommon structural disorder with heterogenous manifestations and elusive pathophysiology. Our aim was to investigate esophageal motility and associated symptom profiles in patients with ED based on high-resolution impedance manometry (HRIM).
Methods: Consecutive patients with ED referred to our motility laboratory between 2015 to 2022 were identified in our electronic database.
Transabdominal Management of Epiphrenic Diverticula in the Setting of Achalasia: A Single-center Review.
Surg Laparosc Endosc Percutan Tech
December 2023
Division of Thoracic and Upper Gastrointestinal Surgery, Montreal General Hospital, McGill University Health Centre, Montreal, Quebec, Canada.
Background: The perioperative and functional outcomes of patients with epiphrenic diverticula (ED) on a background of achalasia managed via a minimally invasive transabdominal approach are under-reported. We describe our center's experience over 10 years of treating such patients.
Methods: A single-center, retrospective chart of a prospectively maintained hospital database was performed.
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