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Nail Unit Melanoma: Uncommon Presentations to Keep in Mind.
Skin Appendage Disord
December 2024
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Dermatology Department, Mexico City, Mexico.
Introduction: This article presents a case of nail unit melanoma (NUM), highlighting the unusual clinical presentations as those originating from the hyponychium. We discuss how dermoscopy is an essential tool for this pigmented lesion, and how the lack of a standardized guide for NUM underscores the importance of personalized approaches to ensure the best possible outcomes.
Case Presentation: A 72-year-old woman presented with a melanocytic lesion on her right second finger, characterized by a hyperpigmented macule with irregular borders and a heterogeneous distribution of pigment.
Uncommon and Unusual Variants of Autoimmune Bullous Diseases.
Indian Dermatol Online J
August 2024
Department of Dermatology, Venereology and Leprology, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Article Synopsis
- Autoimmune blistering diseases (AIBDs) are skin conditions caused by the body's immune system attacking certain proteins, leading to blister formation, and can be categorized into intraepidermal and subepidermal types.
- The objective of this review is to raise awareness about rare and uncommon AIBD variants, such as pemphigus herpetiformis and anti-laminin 332 pemphigoid, among others.
- By discussing these unusual variants, the review aims to assist healthcare professionals in the early diagnosis and treatment of these conditions.
Update on primary cutaneous T-cell lymphomas rare subtypes.
Dermatol Reports
May 2024
Inter-Hospital Pathology Division, IRCCS Multimedica, Milan, Italy.
Rare subtypes of cutaneous T-cell lymphomas (CTCL) include four entities, primary cutaneous γδ T-cell lymphoma, primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma, and primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorders, primary cutaneous acral CD8+ T-cell lymphoma, which were previously considered provisional and are now included in the new 5 World Health Organization classification of hematolymphoid tumors as distinct entities. An updated summary of the clinical, histological, and genomic characteristics of these uncommon CTCL subtypes is given in this review, with a focus on the growing body of knowledge regarding their classification and possible treatment strategies.
View Article and Find Full Text PDFTinea Nigra: Clinical and Diagnostic Guidance.
Cureus
August 2024
Medical Benefits, Mexican Social Security Institute, Campeche, MEX.
Article Synopsis
- - Tinea nigra is a rare fungal infection that mainly affects the palms and soles, presenting as painless dark spots, which can be mistaken for other skin lesions.
- - A case study of a 64-year-old woman from Yucatan, Mexico, diagnosed with tinea nigra through skin scrapings showed pigmented yeast, leading to successful treatment with topical ketoconazole.
- - The report emphasizes the importance of thorough examinations and a proposed diagnostic algorithm to improve recognition and treatment of tinea nigra, particularly in areas where it is less common.
Acral Metastasis to the Hand as the Primary Presentation of Malignancy.
J Hand Surg Glob Online
July 2024
Rothman Orthopaedic Institute, Sidney Kimmel Medical College, Thomas Jefferson University Hospital, Philadelphia, PA.
Metastatic hand tumors are uncommon but important to include in the differential diagnosis for hand masses. In this study, we report the case of a patient presenting initially with hand pain and swelling with no other pertinent medical history except for an extensive smoking history. Subsequent mass biopsy and work-up revealed metastatic lung cancer.
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