Background: In recent years, transplantation, a specific area of medicine, has achieved more and more support and acceptance among different nations around the world. However, there are still many ethical, moral, and legal barriers related to this form of treatment of end-stage organ failures. The aim of this study was to investigate the knowledge and opinions of rural residents about organ transplantation.

Material And Methods: The research method is a diagnostic survey of 395 rural residents of selected villages of the region of Podlasie, located in north-east Poland. The research tool used to carry out the study was the authors' questionnaire.

Results: Organs procurement and transplantation from deceased donors are accepted by 72.6% of respondents. About 60% of the respondents would agree to organ donation for transplantation from the members of their family after death and 65.3% of the residents would be donors after their death. Half of the respondents (55.9%) believe that the final decision as to the donation of organs from a deceased person should be taken by the family. A positive attitude towards organ transplantation was expressed by 67.6% of respondents.

Conclusions: Inhabitants of rural areas mostly agree with procurement of organs from the deceased and also from living donors. However, the enthusiasm and goodwill associated with the transplantation of organs after death diminished when the problem affects members of the family. Positive attitude about transplantation is related to age and level of the education.

Download full-text PDF

Source
http://dx.doi.org/10.12659/AOT.892659DOI Listing

Publication Analysis

Top Keywords

organ donation
8
donation transplantation
8
residents selected
8
selected villages
8
rural residents
8
members family
8
organs deceased
8
family positive
8
positive attitude
8
transplantation
7

Similar Publications

Introduction: Pediatric liver transplantation provides substantial survival benefit. An emphasis on value-based practices has become a central theme in many surgical fields, but have not been well-studied in pediatric transplantation. Given an increasing focus on optimizing outcomes while containing costs, defining value in pediatric liver transplantation warrants investigation.

View Article and Find Full Text PDF

Background: Patients with end-stage kidney disease often prefer home-based dialysis due to higher self-efficacy, which relates to improved medical treatment adherence. Kidney transplantation (KT) success depends on adhering to immunosuppressive medication post-transplant.

Objectives: To investigate whether adherence post-kidney transplantation (KT) and patients' attitudes toward immunosuppression were influenced by their prior dialysis type modality.

View Article and Find Full Text PDF

Background: Intestinal transplantation (ITx) represents the only curative option for patients with irreversible intestinal failure. Nevertheless, its rejection rate surpasses that of other solid organ transplants due to the heightened immunological load of the gut. Regulatory T-cells (Tregs) are key players in the induction and maintenance of peripheral tolerance, suggesting their potential involvement in modulating host vs.

View Article and Find Full Text PDF

Immunologic bile duct destruction is a pathogenic condition associated with vanishing bile duct syndrome (VBDS) after liver transplantation and hematopoietic stem-cell transplantation. As the bile acid receptor sphingosine 1-phosphate receptor 2 (S1PR2) plays a critical role in recruitment of bone marrow-derived monocytes/macrophages to sites of cholestatic liver injury, S1PR2 expression was examined using cultured macrophages and patient tissues. Bile canaliculi destruction precedes intrahepatic ductopenia; therefore, we focused on hepatocyte S1PR2 and the downstream RhoA/Rho kinase 1 (ROCK1) signaling pathway and bile canaliculi alterations using three-dimensional hepatocyte culture models that form obvious bile canaliculus-like networks.

View Article and Find Full Text PDF

Low agreement and frequent invalid controls in two SARS-CoV-2 T-cell assays in people with compromised immune function.

PLoS One

January 2025

Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland.

T-cell response plays an important role in SARS-CoV-2 immunogenicity. For people living with HIV (PWH) and solid organ transplant (SOT) recipients there is limited evidence on the reliability of commercially available T-cell tests. We assessed 173 blood samples from 81 participants (62 samples from 35 PWH; 111 samples from 46 SOT recipients [lung and kidney]) with two commercial SARS-CoV-2 Interferon-γ (IFN-γ) release assays (IGRA; SARS-CoV-2 IGRA by Euroimmun, and IGRA SARS-CoV-2 by Roche).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!