The purpose of this study was to compare oral health between adolescents who are recovering drug addicts and adolescents who report not having used psychoactive substances. A retrospective observational Case-Control study was conducted on 60 subjects per group, aged 15 to 25 years, paired according to sex, age and educational vulnerability. Dental and sialochemical examinations were used to determine oral health/disease/care indicators. Psychoactive substance use habits were obtained from clinical records. DMFT index for Case adolescents was 8.58}4.34, doubling the mean value for the Control group, which was 4.33}4.30. CPI was compatible with gingival-periodontal health in 45% of the Control subjects, but only 20% in the Case group. CPI categories 2 and 3 had different distributions according to the study group, with CPI2=33%, CPI3=0% for the case group and CPI2=57%; CPI3=5% for the control group. Mean values for stimulated saliva for Case and Control groups, respectively, were: salivary flow (ml/min) 1.42}1.08; 0.98}0.41, salivary pH 6.96}0.33 6.86}0.27, and buffer capacity expressed as final pH, 6.73}0.29, 6.61}0.28. Wilcoxon's test for independent samples showed significant differences (p<0.05) between Case and Control for the variables White Spot, Non-Cavitated Carious Lesions, Cavitated Carious Lesions, DMFT, Components D and M, Salivary Flow and Buffer Capacity. There was significant association between the D component in DMFT and use of psychoactive substances, both in single drug and polydrug users. Oral component status was worse in recovering drug addicts than in non-users of psychoactive substances.
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http://dx.doi.org/10.1590/S1852-48342015000100007 | DOI Listing |
Med Sci Monit
January 2025
Department of Oral Implantology, The Affiliated Stomatology Hospital, Jiangxi Medical College, Nanchang University, Jiangxi Province Key Laboratory of Oral Biomedicine, Jiangxi Province Clinical Research Center for Oral Disease, Nanchang, Jiangxi, China.
BACKGROUND This study included 32 patients with single missing teeth and alveolar bone defects and aimed to compare outcomes from guided bone regeneration with a gelatin/polylactic acid (GT/PLA) barrier membrane and a Guidor® bioresorbable matrix barrier dental membrane. MATERIAL AND METHODS A total of 32 participants were recruited in the clinical study, with single missing teeth and alveolar bone defects, requiring guided bone regeneration (32 missing teeth in total). They were randomly divided into the GT/PLA membrane group (experimental) and Guidor® membrane group (control) by the envelope method (n=16).
View Article and Find Full Text PDFAnn Surg Oncol
January 2025
Department of Surgery, Duke University Medical Center, Durham, NC, USA.
Background: Bilateral risk-reducing mastectomies (RRMs) have been proven to decrease the risk of breast cancer in patients at high risk owing to family history or having pathogenic genetic mutations. However, few resources with consolidated data have detailed the patient experience following surgery. This systematic review features patient-reported outcomes for patients with no breast cancer history in the year after their bilateral RRM.
View Article and Find Full Text PDFMol Cell Biochem
January 2025
Department of Urology, Guizhou Provincial People's Hospital, Guiyang, 550002, China.
Selenium, an essential trace mineral for health, has seen a rise in clinical trials over the past nearly 5 decades. Our aim here is to provide a comprehensive and concise overview of selenium clinical trials from 1976 to 2023. Overall, the evolution of selenium clinical trials over 48 years has advanced through phases of emergence, prosperity, and either stability or transition.
View Article and Find Full Text PDFBiol Trace Elem Res
January 2025
College of Architecture and Environment, Sichuan University, Chengdu, 610065, China.
Exposure to vanadium (V) occurs through the ingestion of contaminated water, polluted soil, V-containing foods and medications, and the toxicity and absorption during the small intestine phase after oral ingestion play crucial roles in the ultimate health hazards posed by V. In this study, the human colon adenocarcinoma (Caco-2) cells were selected as an intestinal absorption model to investigate the uptake and cytotoxicity of vanadyl sulfate (VOSO) and sodium orthovanadate (NaVO). Our results confirmed the cytotoxic effects of V(IV) and V(V) and revealed a greater toxicity of V(IV) than V(V) towards Caco-2 cells.
View Article and Find Full Text PDFEur Geriatr Med
January 2025
School of Health Sciences, Fukushima Medical University, Fukushima, Japan.
Purpose: This cross-sectional study aimed to clarify the relationship between dysphagia and social isolation among community-dwelling older people.
Methods: The study participants were 238 community-dwelling older people (168 women; mean age, 74.0 ± 5.
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