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Regioselective Suzuki couplings of non-symmetric dibromobenzenes: alkenes as regiochemical control elements. | LitMetric

Regioselective Suzuki couplings of non-symmetric dibromobenzenes: alkenes as regiochemical control elements.

Org Biomol Chem

Department of Chemistry, 153 Gilbert Hall, Corvallis, OR 97333, USA.

Published: June 2015

The regiochemical outcome of Suzuki couplings of non-symmetric dibromobenzenes is investigated. Selectivities are dependent on the proximity of the bromine atom to alkene substituents, not on steric or electronic effects. Extension to a one-pot three-component Suzuki reaction leads to efficient terphenyl syntheses.

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Source
http://dx.doi.org/10.1039/c5ob00717hDOI Listing

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