Introduction: The Psychomotor Vigilance Test (PVT) measures effects of fatigue from sleep loss and circadian misalignment on sustained vigilance performance. To promote PVT use in field environments, a 5-min PVT version has been implemented on a personal digital assistant (PDA) with a touch screen. The present laboratory study was conducted to validate this PVT against a standard 10-min laptop PVT across 38 h of total sleep deprivation (TSD).
Methods: Following a baseline sleep night, subjects underwent 38 h of TSD, during which they performed the PVT every hour, alternating between the two test platforms. The study concluded with a night of recovery sleep.
Results: The primary outcome was the number of PVT lapses (reaction times > 500 ms). Both PVT platforms showed significant effects for the number of lapses across TSD test times involving an increase with time awake modulated by circadian rhythm. Laptop PVT lapses across test times exhibited a large effect size (f2 = 0.36), whereas PDA PVT lapses exhibited a medium effect size (f2 = 0.17). The laptop PVT showed a significant effect for the number of false starts during TSD similar to the temporal profile of lapses, while the PDA PVT had false starts throughout the TSD period.
Discussion: The 5-min PDA PVT provided performance testing functionality and results comparable to the 10-min laptop PVT. The number of PDA PVT lapses tracked fatigue similarly to the laptop PVT lapses, albeit with smaller average ranges and effect sizes.
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http://dx.doi.org/10.3357/AMHP.4165.2015 | DOI Listing |
Cureus
July 2024
Clinical Research, TrialGuna Private Limited, Bengaluru, IND.
Background and objectives Stadice is a proprietary herbal ingredient preparation standardized to mangiferin, developed to support cognitive wellness in healthy adults. extract and its active constituent, mangiferin were known for its positive cognitive health benefits at experimental levels. This was an attempt to evaluate the clinical efficacy and safety of Stadice on healthy subjects.
View Article and Find Full Text PDFJ Hum Reprod Sci
September 2022
Department of Reproductive Medicine, Jindal Hospital, Meerut, Uttar Pradesh, India.
Background: Infertility is a world-wide problem and one third females. Over the years, anti-mullerian hormone (AMH) has emerged as a major marker of ovarian reserve. There is also increasing interest in determining the factors which can impact AMH levels.
View Article and Find Full Text PDFAnalyst
November 2022
Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai, India.
We report the development of a portable absorption (PortAbs)-based pathogen nucleic acid detection system using peptide nucleic acid (PNA) and a cyanine dye, DiSc(5). When the dye binds to the PNA-DNA hybrid, it results in a characteristic ∼110 nm shift in the dye absorbance, which we measure using PortAbs. The protocol involves amplification of the target DNA, PNA-DNA hybridization and dye complexing steps followed by absorption measurement.
View Article and Find Full Text PDFAerosp Med Hum Perform
May 2020
Given the challenges of collecting reliable Psychomotor Vigilance Task (PVT) data in the field, this study compared a 3-min PVT on a hand-held device and wrist-worn device vs. a standardized laptop. The experiment utilized a randomized, repeated-measures design.
View Article and Find Full Text PDFJ Neurosci Methods
July 2018
Biotechnology High Performance Computing Software Applications Institute (BHSAI), Telemedicine and Advanced Technology Research Center (TATRC), U.S. Army Medical Research and Materiel Command (USAMRMC), ATTN: MCMR-TT, 504 Scott Street, Fort Detrick, MD 21702, USA.
Background: The psychomotor vigilance task (PVT) has been widely used to assess the effects of sleep deprivation on human neurobehavioral performance. To facilitate research in this field, we previously developed the PC-PVT, a freely available software system analogous to the "gold-standard" PVT-192 that, in addition to allowing for simple visual reaction time (RT) tests, also allows for near real-time PVT analysis, prediction, and visualization in a personal computer (PC).
New Method: Here we present the PC-PVT 2.
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