Capillary muscle.

Proc Natl Acad Sci U S A

Laboratoire d'Hydrodynamique de l'X, UMR 7646 du CNRS, École Polytechnique, 91128 Palaiseau, France; and Physique et Mécanique des Milieux Hétérogènes, UMR 7636 du CNRS, École Supérieure de Physique et de Chimie Industrielles, 75005 Paris, France

Published: May 2015

The contraction of a muscle generates a force that decreases when increasing the contraction velocity. This "hyperbolic" force-velocity relationship has been known since the seminal work of A. V. Hill in 1938 [Hill AV (1938) Proc R Soc Lond B Biol Sci 126(843):136-195]. Hill's heuristic equation is still used, and the sliding-filament theory for the sarcomere [Huxley H, Hanson J (1954) Nature 173(4412):973-976; Huxley AF, Niedergerke R (1954) Nature 173(4412):971-973] suggested how its different parameters can be related to the molecular origin of the force generator [Huxley AF (1957) Prog Biophys Biophys Chem 7:255-318; Deshcherevskiĭ VI (1968) Biofizika 13(5):928-935]. Here, we develop a capillary analog of the sarcomere obeying Hill's equation and discuss its analogy with muscles.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443323PMC
http://dx.doi.org/10.1073/pnas.1419315112DOI Listing

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