Liver cancer has a poor prognosis. Our recent study demonstrates that hyper-IL-15, composed of IL-15 and the sushi domain of IL-15 receptor α chain, provides an effective therapy against well-established metastatic and autochthonous liver cancers in mouse models by triggering activation and expansion of hepatic CD8 T cells.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292759 | PMC |
| http://dx.doi.org/10.4161/21624011.2014.963409 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Transformative characteristics of aquatic and soil organic matter in a constructed wetland consisting of Acorus, Nuphar, and Typha ponds.
Sci Total Environ
December 2024
Department of Environmental Engineering, College of Art, Culture, and Engineering, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon-si, Gangwon-do 24341, Republic of Korea; Department of Integrated Energy and Infrasystem, Kangwon National University, Kangwondaehak-gil, 1, Chuncheon-si, Gangwon-do 24341, Republic of Korea. Electronic address:
Article Synopsis
- The study explored how dissolved organic matter (DOM) transforms in constructed wetlands (CWs) and its interaction with soil organic matter (SOM) during various treatment stages.
- Through methods like water quality assessments and molecular analyses, findings showed that anaerobic decomposition in the Typha pond significantly increased dissolved organic carbon (DOC) levels, indicating the role of microbial activity.
- The research highlighted that DOM in CWs interacts with organic fractions from both water and soil, influencing water quality improvement and offering insights for better CW design and management for wastewater treatment.
Detection of DNA Using Conventional Polymerase Chain Reaction in Canine Abortion, Stillbirth, and Neonatal Mortality Cases in Central Italy.
Pathogens
November 2024
School of Biosciences and Veterinary Medicine, University of Camerino, Via Circonvallazione 93/95, 62024 Matelica, MC, Italy.
Article Synopsis
- - The study investigated the role of a specific microorganism in canine infertility, analyzing 114 cases of abortion, stillbirth, and neonatal mortality in dogs from Central Italy, but findings were mixed and only a small percentage tested positive.
- - Out of the cases studied, 6.14% showed a positive result for the microorganism's DNA, with some cases also identifying other pathogens known to cause infertility and neonatal issues.
- - The presence of the microorganism in the female reproductive tract suggests it may be a normal part of the genital microflora, rather than a direct cause of abortion or neonatal death in most cases.
An indigenous microalgal pool containing Klebsormidium sp. K39 as a stable and efficacious biotechnological strategy for Escherichia coli removal in urban wastewater treatment.
J Sci Food Agric
January 2025
Department of Agriculture, Food and Environment, University of Catania, Catania, Italy.
Background: In recent decades the demand for freshwater has drastically increased as a consequence of population growth, economic development, climate change and pollution. Therefore, any strategy for wastewater treatment can play a role in alleviating the pressure on freshwater sources.
Results: In the present study an autochthonous microalgal pool (MP), isolated from a constructed wetland, was proposed as an alternative to the secondary treatment of an urban wastewater treatment system.
Phenolic profile, antioxidant capacity and oxidoreductase enzyme activity in autochthonous grape varieties from Bosnia and Herzegovina.
Nat Prod Res
September 2024
Institute for Multidisciplinary Research, University of Belgrade, Belgrade, Serbia.
The variability of phenolic compounds among grape varieties has an important role in selecting winemaking techniques, but the use of phenolic profiles for quality control is still fragmented and incomplete. Given the recent climate change and global warming, biochemical characterisation of secondary metabolites in autochthonous grape varieties is a very important factor for their preservation and sustainable agriculture. Two autochthonous grape varieties from the western Herzegovina region in Bosnia and Herzegovina have been selected for the research targeting at the evaluation of their phenolic profiles, antioxidant activities, and the correlation with oxidoreductase enzymes polyphenol oxidase and Class III peroxidase, in different berry tissues.
View Article and Find Full Text PDFPostharvest dehydration of red grapes: impact of temperature and water-loss conditions on free and glycosylated volatile metabolites of exocarp and epicarp of Nebbiolo and Aleatico varieties.
J Sci Food Agric
January 2025
Department of Agricultural Sciences, Division of Vine and Wine Sciences, University of Naples Federico II, Avellino, Italy.
Article Synopsis
- Postharvest dehydration of grapes significantly affects the metabolism and aromatic qualities of passito wines, especially in relation to specific grape varieties and winemaking practices.
- In a study, it was found that for Nebbiolo grapes, weight loss during dehydration primarily influenced free volatile compounds, while low temperatures increased glycosylated volatile terpene content, whereas for Aleatico, both weight loss and temperature affected the aromatic compounds substantially.
- The findings suggest that optimizing dehydration conditions can enhance the preservation of grape aromas for high-quality wines, while also improving energy efficiency and sustainability in production processes.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!