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Immunotherapy of metastatic and autochthonous liver cancer with IL-15/IL-15Rα fusion protein. | LitMetric

Liver cancer has a poor prognosis. Our recent study demonstrates that hyper-IL-15, composed of IL-15 and the sushi domain of IL-15 receptor α chain, provides an effective therapy against well-established metastatic and autochthonous liver cancers in mouse models by triggering activation and expansion of hepatic CD8 T cells.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292759PMC
http://dx.doi.org/10.4161/21624011.2014.963409DOI Listing

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