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Distribution of Airway Findings in ANCA-Associated Vasculitis: A 20-Year Observational Analysis.
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Department of Internal Medicine, Division of Rheumatology, Mayo Clinic, Jacksonville, FL 32224, USA.
Pulmonary involvement is commonly observed in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), presenting with manifestations such as diffuse alveolar hemorrhage, inflammatory infiltrates, pulmonary nodules, and tracheobronchial disease. We aimed to identify distinct subgroups of tracheobronchial disease patterns in patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) using latent class analysis (LCA), and to evaluate their clinical characteristics and outcomes. We conducted a retrospective cohort study using electronic medical records of patients aged >18 years diagnosed with AAV and tracheobronchial disease between 1 January 2002 and 6 September 2022.
View Article and Find Full Text PDFPersistent Risk of Pulmonary Embolism in Acute Pancreatitis Despite Prophylactic Anticoagulation.
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Internal Medicine, Creighton University School of Medicine, Phoenix, USA.
Acute pancreatitis, a sudden inflammatory condition, can lead to a hypercoagulable state resulting in complications such as deep vein thrombosis (DVT) or pulmonary embolism (PE). This case report discusses a unique presentation of a massive PE in a patient with acute pancreatitis despite being on appropriate prophylactic anticoagulation. A 27-year-old man presented with acute abdominal pain, nausea, and vomiting.
View Article and Find Full Text PDFMechanical Pulmonary Thrombectomy: A Case Report on a Life-Saving Intervention in Acute Pulmonary Embolism.
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Department of Interventional Radiology, Worcestershire Acute Hospital NHS Trust, Worcester, GBR.
A 69-year-old male presented to the emergency department with sudden shortness of breath, three weeks after recovering from a COVID-19 infection. Despite having no significant prior medical history, the patient rapidly deteriorated, suffering a cardiac arrest. He was resuscitated and diagnosed with a massive saddle pulmonary embolism, confirmed via echocardiogram and computed tomography pulmonary angiography (CTPA).
View Article and Find Full Text PDFUse of Extracorporeal Membrane Oxygenation-Facilitated Large-Bore Catheter Embolectomy in the Treatment of Acute Pulmonary Embolism Complicated by Shock.
Tex Heart Inst J
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Department of Cardiology, St John University Hospital, Detroit, Michigan.
This article reports the case of a 42-year-old man who presented with a saddle pulmonary embolus complicated by normotensive cardiogenic shock. The patient was first stabilized with venoarterial extracorporeal membrane oxygenation. Then, while the patient was still on extracorporeal membrane oxygenation, thrombectomy with a large-bore catheter device was performed that resulted in a large decrease in pulmonary artery pressures and a clinically significant increase in cardiac index, with rapid clinical improvement.
View Article and Find Full Text PDFManagement of Saddle Pulmonary Embolism in the Context of Heparin-Induced Thrombocytopenia and Granulomatosis With Polyangiitis.
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Respiratory Medicine, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, GBR.
Article Synopsis
- Heparin-induced thrombocytopenia (HIT) is a serious complication from heparin therapy that leads to a low platelet count and increased risk of blood clots.
- A case study involved a 65-year-old woman with a history of granulomatosis with polyangiitis (GPA) and kidney issues, who developed a significant pulmonary embolism.
- The case underscores the complexities of treating pulmonary embolism in patients with HIT, highlighting the importance of tailored anticoagulation approaches and teamwork among healthcare providers.
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