AI Article Synopsis
- The study aimed to validate the Endometriosis Fertility Index (EFI) and investigate pregnancy rates following surgical and assisted reproductive treatments in patients with infertility due to endometriosis.
- Conducted over eight years in a university hospital, the research involved 412 patients who underwent laparoscopic surgery for endometriosis, followed by fertility treatments.
- Findings showed a strong correlation between the EFI and spontaneous pregnancy rates, with an impressive cumulative pregnancy rate of 78.8% at 18 months, particularly benefiting those with lower EFI scores.
Article Abstract
Objective: To show an external validation of the Endometriosis Fertility Index (EFI) and to observe cumulated pregnancy rates after infertility management combining surgery and assisted reproductive technologies (ART).
Design: Observational study from January 2004 to December 2012.
Setting: Tertiary-care university hospital and ART center.
Patient(s): Four hundred twelve infertile and endometriotic patients after laparoscopic surgery.
Intervention(s): Surgical diagnosis and treatment followed by spontaneous fertility or ART management.
Main Outcome Measure(s): Spontaneous pregnancy rates and cumulative (spontaneous and ART) pregnancy rates according to the EFI.
Result(s): A significant relationship between EFI and spontaneous pregnancy rates was observed at 12 months (P=.001). The least function score and complete removal of endometriotic lesions and pelvic adhesions were significantly associated with spontaneous pregnancy (P=.006). Cumulative pregnancy rate at 18 months was 78.8%. ART benefits for pregnancy rates were higher for patients with poor EFI.
Conclusion(s): External validation of the EFI in a French population was demonstrated. Combining surgery for endometriosis and ART led to a 78.8% pregnancy rate at 18 months after surgery.
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| http://dx.doi.org/10.1016/j.fertnstert.2015.03.028 | DOI Listing |
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