Erectile Dysfunction Is Common among Patients with Gout.

Objective: To determine whether men with gout may have an increased prevalence of erectile dysfunction (ED) as compared with men without gout.

Methods: In this cross-sectional study, men aged 18-89 presenting to the rheumatology clinic between August 26, 2010, and May 13, 2013, were asked to participate. The presence of ED was determined by the Sexual Health Inventory in Men (SHIM). SHIM classifies ED into 1 of 5 categories: absent (22-25), mild (17-21), mild to moderate (12-16), moderate (8-11), and severe (1-7). Patient's history, physical examination, and recent laboratory studies were reviewed as well. Descriptive statistics and subgroup analyses were used to summarize the data.

Results: Of the 201 men surveyed, 83 had gout (control, n = 118). A significantly greater proportion of patients with gout (63, 76%) had ED versus patients without gout (60, 51%, p = 0.0003). A significantly greater proportion of patients with gout (22, 26%) had severe ED versus patients without gout (17, 15%, p = 0.04). Patients with gout had an average SHIM score of 14.4 versus 18.48 in patients without gout (p < 0.0001). There was a statistically significant association between gout and ED. The association remained significant after adjustment for age, hypertension, diabetes, and obesity.

Conclusion: ED is present in most men with gout and is frequently severe. We propose that patients with gout be routinely screened for ED.