Seventy nine patients with essential hypertension were studied. Group 1 showed profound changes in hemorheological parameters, Group 2 exhibited moderate changes in this system. A more severe course of essential hypertension was found in patients from Group 1. The clinical picture of the disease was more favorable, and antihypertensive therapy was more efficient in patients from Group 2. It was concluded that the initial rheological background and the status of the hemolytic system largely governed the clinical course of essential hypertension and the efficacy of the therapy.

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