Objective: This study was designed to compare the efficacy of crystallized phenol method with Limberg flap in pilonidal sinus treatment.
Material And Methods: Patients with a diagnosis of pilonidal sinus disease treated with surgical excision + Limberg rhomboid flap technique and crystallized phenol method between 2010-2011 in the Şevket Yılmaz Training and Research Hospital, Department of General Surgery were evaluated retrospectively. Patients' age, sex, length of hospital stay, complications and recurrence rates were evaluated.
Results: Eighty eight percent of patients were male and mean age was 26.84±6.41 in the Limberg group, and 24.72±5.00 in the crystallized phenol group. Sinus orifice locations and nature, and duration of symptoms before surgery were similar in the two groups. Length of hospital stay in the Limberg group was 1.46±0.61 days; whereas all patients in the crystallized phenol group were discharged on the same day. Infection, hematoma, wound dehiscence, and cosmetic problems were significantly higher in the Limberg group. There was no difference between the two groups in terms of recurrence and seroma formation.
Conclusion: The less invasive method of crystallized phenol application may be an alternative approach to rhomboid excision and Limberg flap in patients with non-complicated pilonidal sinus disease, yielding acceptable recurrence rates.
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http://dx.doi.org/10.5152/UCD.2013.2457 | DOI Listing |
Food Sci Nutr
December 2024
Food Biotechnology Department, Instituto de la Grasa (CSIC) Campus Universitario Pablo de Olavide Seville Spain.
The process of biofilm formation during table olive fermentation is crucial to turning this fermented vegetable into a probiotic food. Some phenolic compounds have been described as important quorum-sensing molecules during biofilm development. The present in vitro study examined the effects of three phenolic compounds widely found in table olive fermentations (Oleuropein 0-3000 ppm, Hydroxytyrosol 0-3000 ppm, and Tyrosol 0-300 ppm) on the development of single biofilm by diverse microorganisms isolated from table olives ( 13B4, Lp119, and LPG1; Lp15 and LAB23; and yeasts Y12, Y13, and Y18).
View Article and Find Full Text PDFActa Crystallogr E Crystallogr Commun
October 2024
Department of Chemistry & Biochemistry California State Polytechnic University, Pomona 3801 W Temple Ave Pomona CA 91768 USA.
In the title compound, CHN·2CHNO, 4-nitro-phenol and 4,4'-bi-pyridine crystallized together in a 2:1 ratio in the space group 2/. There is a hydrogen-bonding inter-action between the nitro-gen atoms on the 4,4'-bi-pyridine mol-ecule and the hydrogen atom on the hydroxyl group on the 4-nitro-phenol, resulting in trimolecular units. This structure is a polymorph of a previously reported structure [Nayak & Pedireddi (2016 ▸).
View Article and Find Full Text PDFJ Med Chem
December 2024
Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560012, India.
FadD32, a fatty acyl-AMP ligase, plays an indispensable role in mycobacterial mycolic acid synthesis and is a validated target for tuberculosis (TB) drug development. The crystal structure of (Mtb)FadD32 has laid the foundation of structure-based drug discovery against this crucial enzyme. Here, we screened the "isoxazole" scaffold containing molecules against MtbFadD32 and identified a compound 2,4-dibromo-6-[3-(trifluoromethyl)-1,2-oxazol-5-yl]phenol (M1) with specific inhibitory activity against Mtb.
View Article and Find Full Text PDFFront Plant Sci
December 2024
Department of Horticultural Sciences, Texas A&M University, College Station, TX, United States.
Phytochromes (PHYs) play a dual role in sensing light spectral quality and temperature. PHYs can interconvert between the active P form and inactive P form upon absorption of red (R) and far-red (FR) light (Photoconversion). In addition, active P can be converted to inactive P in a temperature-dependent manner (Thermal Reversion).
View Article and Find Full Text PDFMicrob Pathog
December 2024
University of Kragujevac, Faculty of Science, Department of Biology and Ecology, Radoja Domanovića 12, 34000, Kragujevac, Serbia. Electronic address:
Biofilm is a surface-attached community of bacterial cells implicated in the pathogenesis of chronic infections and is highly resistant to antibiotics. New alternatives for controlling bacterial infections have been proposed focusing on the therapeutic properties of medicinal plants. Achillea millefollium (Yarrow) is a widespread plant species that is widely used in traditional medicine, especially for wound healing.
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