Background: The bacteria Orientia tsutsugamushi is the causative agent of scrub typhus, mite-borne disease, which causes an acute febrile illness in patients. An epidemiologic study was conducted to understand the characteristics of scrub typhus in South Korea.

Findings: Reporting of tsutsugamushi disease is mandatory in South Korea since 1994. To investigate the prevalence of tsutsugamushi disease from 2001 to 2013, medical records from the Korea Center for Disease Control and Prevention were reviewed. In total, 70,914 cases were reported during 2001-2013. Of these, 37.16% (26,349) were male and 62.84% (44,565) were female. The highest number of cases was in the 60-69-year-old age group (19,484; 27.48%), and 72.22% (51,212) were in the 50-79-year-old age group. There were 65,100 cases (91.80%) reported during October (24,964; 35.20%) and November (40,136; 56.60%). An almost four-fold increase in the number of patients was observed in 2013 (10,485 cases) compared to 2001 (2,637 cases). The highest number of patients was reported in the Jeonbuk (9,425; 13.29%) and lowest in the Jeju (362; 0.51%).

Conclusions: A rapid increase in the incidence of patients with tsutsugamushi disease was observed in most areas from 2001 to 2013, with the majority of cases reported in the western and southern coast.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416255PMC
http://dx.doi.org/10.1186/s13071-015-0858-6DOI Listing

Publication Analysis

Top Keywords

scrub typhus
12
tsutsugamushi disease
12
typhus south
8
south korea
8
2001 2013
8
cases reported
8
highest number
8
age group
8
number patients
8
cases
6

Similar Publications

Double-Stranded RNA-Based Method for Diagnosing Severe Fever with Thrombocytopenia.

J Clin Med

December 2024

Department of Internal Medicine, Division of Infectious Disease, Soonchunhyang University Hospital, Cheonan 31151, Republic of Korea.

: This study explores the potential of using elevated levels of blood double-stranded RNA (dsRNA) as a diagnostic tool for severe fever with thrombocytopenia syndrome (SFTS) infection. : Blood samples from SFTS patients were collected, dsRNA was purified, and total dsRNA expression was quantitatively analyzed using a spiropyran-based method. Comparative analysis was performed using blood samples from healthy individuals and scrub typhus patients with similar symptoms.

View Article and Find Full Text PDF

A Case Report of Pediatric Scrub Typhus Presenting as Acalculous Cholecystitis During the Non-Epidemic Season Without Eschar.

Travel Med Infect Dis

January 2025

Second Department of Infectious Disease, Kunming Children's Hospital, Kunming, Yunnan, China; Yunnan Key Specialty of Pediatric Infection (Training and Education Program)/Kunming Key Specialty of Pediatric Infection; Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, China. Electronic address:

View Article and Find Full Text PDF

Scrub typhus (ST) is an emerging public health concern in India. Despite being treatable, 20-30% of acute febrile illnesses (AFI) progress to encephalitis in endemic regions. This study aimed to identify early markers for encephalitis development in children hospitalized with AFI and positive Orientia tsutsugamushi (Ots) serology.

View Article and Find Full Text PDF

Historical Overview of Tsutsugamushi Disease in Japan before World War II.

Infect Chemother

December 2024

Division of Infectious Diseases, Department of Internal Medicine, Inha University School of Medicine, Incheon, Korea.

Tsutsugamushi disease is a febrile mite-borne disease caused by . Before 1945, this disease had been prevalent in Niigata, Akita, and Yamagata prefectures for centuries, occurring in areas along major rivers in these prefectures every summer about a month after floods. The patients affected were farmers, possibly new settlers on reclaimed lands, who contracted the disease following bites of tiny red bugs.

View Article and Find Full Text PDF

Re-evaluating Presumptive Treatment with Doxycycline/ Azithromycin in Children With Acute Febrile Illness in a Scrub Typhus Endemic Region: A Cross-Sectional Study.

Indian Pediatr

January 2025

ICMR Regional Medical Research Centre, Gorakhpur, Uttar Pradesh, India. Correspondence to: Dr Manoj Murhekar, Director-in-Charge, ICMR-Regional Medical Research Centre, Gorakhpur, Uttar Pradesh, India 273013.

Objective: To estimate the proportion of children with acute febrile illness (AFI) attending the peripheral health facilities in Gorakhpur, Uttar Pradesh, India, due to Orientia tsutsugamushi (Ots) and re-evaluate the strategy of presumptive administration of doxycycline/azithromycin (PDA) to patients with AFI.

Methods: Children aged 2-18 years with AFI attending 16 peripheral health facilities in Gorakhpur, Uttar Pradesh, were enrolled in September 2023. Blood samples were tested for O.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!