Lung particle overload: old school -new insights?

Part Fibre Toxicol

Professor Emeritus of Toxicology, University of Rochester, Department of Environmental Medicine, Rochester, NY, 14642, USA.

Published: April 2015

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419487PMC
http://dx.doi.org/10.1186/s12989-015-0086-4DOI Listing

Publication Analysis

Top Keywords

lung particle
4
particle overload
4
overload school
4
school -new
4
-new insights?
4
lung
1
overload
1
school
1
-new
1
insights?
1

Similar Publications

Inhalation exposure to respirable crystalline silica (RCS) during the fabrication of engineered stone-based kitchen countertops has been on the rise in recent years and has become a significant occupational health problem in the United States and globally. Little is known about the presence of nanocrystalline silica (NCS), i.e.

View Article and Find Full Text PDF

Detection of carcinoembryonic antigen using aggregation-induced emission luminogens empowered triple-format biosensor.

Biosens Bioelectron

December 2024

School of Science and Engineering, Shenzhen Institute of Aggregate Science and Technology, The Chinese University of Hong Kong, Shenzhen, Guangdong 518172, China.

Conventional fluorescent probes with weak fluorescence signals and aggregation-caused quenching effect limits in biomarkers detection, thus requiring many labeled target molecules to combine their output to achieve higher signal-to noise. Here, we harness a "immune-sandwich" based affinity sensor with development of ultrabright aggregation-induced emission luminogens (AIEgens) microspheres as signal reporter. The fabricated sensor can simultaneously permit triple detection formats by naked eye, spectrum, and computer vision counting (termed "NeSCV sensor").

View Article and Find Full Text PDF

Airway microbiota dysbiosis and metabolic disorder in ozone and PM co-exposure induced lung inflammatory injury in mice.

Ecotoxicol Environ Saf

December 2024

School of Public Health, Xinxiang Medical University, Xinxiang, Henan Province 453003, China. Electronic address:

Co-exposure to ground-level ozone (O) and fine particles (PM, ≤ 2.5 µm in diameter) has become a primary scenario for air pollution exposure of urbanites in China. Recent studies have suggested a synergistic effect of PM and O on induction of lung inflammatory injury.

View Article and Find Full Text PDF

Exposure to diesel exhaust is associated with increased risk of cardiovascular and lung disease. Substituting petroleum diesel with renewable diesel can alter emission properties but the potential health effects remain unclear. This study aimed to explore toxicity and underlying mechanisms of diesel exhaust from renewable fuels.

View Article and Find Full Text PDF

Ventilation and features of the lung environment dynamically alter modeled intrapulmonary aerosol exposure from inhaled electronic cigarettes.

Sci Rep

December 2024

Division of Pulmonary and Critical Care, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095-1690, USA.

Electronic cigarettes (e-cigs) fundamentally differ from tobacco cigarettes in their generation of liquid-based aerosols. Investigating how e-cig aerosols behave when inhaled into the dynamic environment of the lung is important for understanding vaping-related exposure and toxicity. A ventilated artificial lung model was developed to replicate the ventilatory and environmental features of the human lung and study their impact on the characteristics of inhaled e-cig aerosols from simulated vaping scenarios.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!