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Diagnosis and management of small-bowel bleeding.
Best Pract Res Clin Gastroenterol
November 2023
Ellen and Pinchas Mamber Institute of Gastroenterology and Hepatology, Emek Medical Center, Afula, Israel; Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel.
Small-bowel (SB) bleeding is a challenging problem for the clinician, presenting many pitfalls in both diagnosis and subsequent treatment. Videocapsule endoscopy (VCE) and device-assisted enteroscopy (DAE) have revolutionized the approach to the patient with SB bleeding, allowing for the endoscopic diagnosis and management of what was previously only a surgical matter. The patients' assessment in SB bleeding is of foremost importance, as treatment success relies on a detailed evaluation of clinical history, suspicion for underlying lesions, and a careful selection and timing of diagnostic and therapeutic tools.
View Article and Find Full Text PDFDouble-balloon enteroscopy-facilitated cyanoacrylate-injection endotherapy of small-bowel varices: an international experience from 2 European tertiary centers (with videos).
Gastrointest Endosc
August 2019
Royal Free Unit for Endoscopy, The Royal Free Hospital and University College London Institute for Liver and Digestive Health, Hampstead, London, UK.
Background And Aims: Small-bowel varices (SBVs) are an uncommon consequence of portal hypertension. Radiologic intervention is usually considered for first-line management. When radiologic intervention is not possible, management options become very limited.
View Article and Find Full Text PDFMid-gut bleeding due to a chronic splanchnic vascular stricture with secondary portal hypertension after gastric bypass.
Endoscopy
January 2016
Department of Gastroenterology, Hepatopancreatology and Digestive Oncology, Université Libre de Bruxelles, Erasme Hospital, Brussels, Belgium.
Dual silencing of long and short Amblyomma americanum acidic chitinase forms weakens the tick cement cone stability.
J Exp Biol
October 2014
Texas A&M University AgriLife Research, Department of Entomology, 2475 TAMU, College Station, TX 77843, USA
This study demonstrates that Amblyomma americanum (Aam) constitutively and ubiquitously expresses the long (L) and short (S) putative acidic chitinases (Ach) that are distinguished by a 210 base pair (bp) deletion in AamAch-S. Full-length AamAch-L and AamAch-S cDNA are 1959 and 1718 bp long, containing 1332 and 1104 bp open reading frames that code for 443 and 367 amino acid residues proteins with the former predicted to be extracellular and the latter intracellular. Both AamAch-L and AamAch-S mRNA are expressed in multiple organs as revealed by qualitative RT-PCR analysis.
View Article and Find Full Text PDFA comparative evaluation of single-balloon enteroscopy and spiral enteroscopy for patients with mid-gut disorders.
Gastrointest Endosc
October 2010
Department of Medicine and Division of Gastroenterology and Hepatology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.
Background: Single-balloon enteroscopy (SBE) and spiral enteroscopy (SE) are recently described device-assisted techniques in endoluminal evaluation of the small bowel. No studies comparing SBE and SE in patients with suspected small-bowel disorders have previously been reported.
Objective: The aims of this study were to compare SBE and SE in terms of diagnostic yield, procedure time, depth of maximal insertion, and complications.
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