Two new compounds of acutacosides 1 and 2, pentasaccharide resin glycosides were isolated from the aerial parts of Argyreia acuta. The core of the two compounds was operculinic acid A, and they were esterfied at the same position, just one substituent group was linked at C-2 of Rha. The absolute configuration of the aglycone in the two compounds was established by Mosher's method, which was (11S)-hydroxyhexadecanoic acid (jalapinolic acid). Their structures were established by a combination of spectroscopic and chemical methods.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/14786419.2015.1030739 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Expression and immobilization of novel N-glycan-binding protein for highly efficient purification and enrichment of N-glycans, N-glycopeptides, and N-glycoproteins.
Anal Bioanal Chem
December 2024
Britton Chance Center for Biomedical Photonics at Wuhan National Laboratory for Optoelectronics - Hubei Bioinformatics & Molecular Imaging Key Laboratory, Systems Biology Theme, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, China.
Article Synopsis
- Comprehensive enrichment of N-glycans and associated molecules is crucial in N-glycomics research to simplify samples, reduce impurities, and enhance analysis quality.
- The research focuses on a specific Fbs1 GYR variant (Fg), which has a strong binding affinity for the core pentasaccharide of N-glycans, making it effective for this purpose.
- The study involved cloning the Fg into a GST-tagged vector for easy purification, resulting in a stable and effective protein that can efficiently isolate N-glycans and their derivatives for analytical applications.
Effect of edaphoclimate on the resin glycoside profile of the ruderal Ipomoea parasitica (Convolvulaceae).
PLoS One
August 2024
Centro de Investigación en Biotecnología (CEIB), Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos, México.
The latex of Ipomoea (Convolvulaceae) is a source of a special kind of acylsugars called resin glycosides, which are highly appreciated because of their biological activities (i.e. laxative, antimicrobial, cytotoxic etc.
View Article and Find Full Text PDFTotal Synthesis of the Purported Structure of Branched Resin Glycosides Merremoside G and H.
Org Lett
January 2024
Department of Chemistry, Pohang University of Science and Technology, Cheongam-Ro 77, Nam-Gu, Pohang, Kyeongbuk 37673, Republic of Korea.
The first total synthesis of the purported structure of branched resin glycosides merremoside G and H is accomplished. A signature step is represented by the sequential transition-metal-catalyzed coupling of stable trisaccharide homoallylic alcohol and monosaccharide alkoxyallene to afford the pentasaccharide skeleton. This strategy is conducted under mild conditions with no need of preactivation.
View Article and Find Full Text PDFResin Glycosides from and Their Synergism with Vinblastine in Cancer Cells.
J Nat Prod
October 2022
Departamento de Farmacia, Facultad de Química and Programa de Maestría y Doctorado en Ciencias Químicas, Universidad Nacional Autónoma de México, Ciudad Universitaria, Mexico City 04510, Mexico.
is a vine native to the north and northeast region of Brazil, where its roots are traded as a depurative and laxative remedy with the name of Brazilian jalap in traditional medicine. Procedures for the isolation, purification by recycling HPLC, and structure elucidation of three undescribed resin glycosides are presented herein. Hamiltonin I () represents a macrocyclic structure of a tetrasaccharide of (11)-hydroxyhexadecanoic acid.
View Article and Find Full Text PDFThe development of a dedicated polymer support for the solid-phase oligosaccharide synthesis.
Chem Commun (Camb)
September 2020
Department of Chemistry and Biochemistry, University of Missouri - St. Louis, One University Boulevard, St. Louis, Missouri 63121, USA.
Reported herein is the development of a novel polystyrene-based resin that we named PanzaGel. The resin was equipped with diethylene glycol-derived cross-linker with the dedicated application to polymer supported glycan synthesis in mind. After investigating its swelling properties and obtaining encouraging data for its chemical and thermal stability we accessed the amenability of PanzaGel to the HPLC-based platform for the automated synthesis.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!