Antifungal activity of silver nanoparticles obtained by green synthesis.

Rev Inst Med Trop Sao Paulo

Grupo de Química de Materiais Avançados, Departamento de Química Analítica e Físico-Química, Universidade Federal do Ceará, Fortaleza, CE, Brazil.

Published: January 2016

Silver nanoparticles (AgNPs) are metal structures at the nanoscale. AgNPs have exhibited antimicrobial activities against fungi and bacteria; however synthesis of AgNPs can generate toxic waste during the reaction process. Accordingly, new routes using non-toxic compounds have been researched. The proposal of the present study was to synthesize AgNPs using ribose as a reducing agent and sodium dodecyl sulfate (SDS) as a stabilizer. The antifungal activity of these particles against C. albicans and C. tropicalis was also evaluated. Stable nanoparticles 12.5 ± 4.9 nm (mean ± SD) in size were obtained, which showed high activity against Candida spp. and could represent an alternative for fungal infection treatment.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435016PMC
http://dx.doi.org/10.1590/S0036-46652015000200011DOI Listing

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