Neutrophile elastase has the capacity to degrade elastin, a protein found in the connective tissue of the lungs. Unchecked elastase leads to pulmonary pathologies. Therefore, the development of elastase inhibitors is currently actively pursued in the therapeutic field. Several triterpenoids have been reported as inhibitors against elastase or its release. Such compounds could be valuable for the design of new drugs. This review is aimed at giving a comprehensive insight into the recent work performed in the field of triterpenoid-induced elastase inhibition.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
elastase inhibitors
8
elastase
6
triterpenoids neutrophil
4
neutrophil elastase
4
inhibitors neutrophile
4
neutrophile elastase
4
elastase capacity
4
capacity degrade
4
degrade elastin
4
elastin protein
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!