AI Article Synopsis
- A new acyclic diterpenoid and a new erythroxan diterpenoid were discovered from Fagonia mollis, along with several other related compounds.
- Structural analysis of these compounds was conducted using 1D and 2D NMR techniques.
- The cytotoxic effects of these isolated compounds were tested on HL-60 cancer cells.
Article Abstract
A new acyclic diterpenoid (1) and a new erythroxan diterpenoid (2), together with 4 erythroxan diterpenoids and 3 triterpenoids, have been isolated from the aerial parts of Fagonia mollis. Their structures were elucidated on the basis of 1D and 2D NMR data. The cytotoxic activity of the isolated compounds was investigated against HL-60 cancer cells.
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View Article and Find Full Text PDFArticle Synopsis
- A new acyclic diterpenoid and a new erythroxan diterpenoid were discovered from Fagonia mollis, along with several other related compounds.
- Structural analysis of these compounds was conducted using 1D and 2D NMR techniques.
- The cytotoxic effects of these isolated compounds were tested on HL-60 cancer cells.
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June 2012
Theodor Bilharz Research Institute, Schistosome Biological Supply Center, Cairo, Imbaba, Egypt.
Context: This study is a continuation of our previous work in which a bioassay screening of 346 methanol extracts from 281 Egyptian plant species was carried out for in vitro schistosomicidal activity.
Objective: Another 309 methanol extracts from 278 plant species were subjected to the bioassay screening using the same technique on viable Schistosoma mansoni Sambon (Schistosomatidae) mature worms in specialized culture medium (Roswell Park Memorial Institute medium 1640) in a trial to discover a source for a schistosomiasis drug from Egyptian flora.
Material And Methods: The methanol plant extracts were tested in vitro against viable S.
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