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Withdrawal of a novel-design duodenoscope ends outbreak of a VIM-2-producing Pseudomonas aeruginosa.
Endoscopy
June 2015
Department of Medical Microbiology and Infectious Diseases, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
Withdrawal of a novel-design duodenoscope ends outbreak of a VIM-2-producing Pseudomonas aeruginosa.
Endoscopy
June 2015
Department of Medical Microbiology and Infectious Diseases, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
Background And Study Aims: Infections are a recognized risk of endoscopic retrograde cholangiopancreatography (ERCP). This paper reports on a large outbreak of VIM-2-producing Pseudomonas aeruginosa that was linked to the use of a recently introduced duodenoscope with a specific modified design (Olympus TJF-Q180V).
Methods: Epidemiological investigations and molecular typing were executed in order to identify the source of the outbreak.
Novel design for a phase IIa placebo-controlled, double-blind randomized withdrawal study to evaluate the safety and efficacy of CNV1014802 in patients with trigeminal neuralgia.
Trials
November 2013
Facial pain unit, Division of Diagnostic, Surgical and Medical Sciences, Eastman Dental Hospital, UCLH NHS Foundation Trust/University College London, 256 Gray's Inn Road, WC1X 8LD, London, UK.
Background: Trigeminal neuralgia (TN) is a rare severe unilateral facial pain condition. Current guidelines in trigeminal neuralgia management recommend sodium channel blockers--carbamazepine or oxcarbazepine--as the first-line treatment. However, the currently available drugs are often associated with poor tolerability resulting in sub-optimal pain control.
View Article and Find Full Text PDF[Comparison between VAMA(®) and Berman(®) cannulas for fibroscopic orotracheal intubation in anaesthetised patients].
Rev Esp Anestesiol Reanim
March 2013
Servicio de Anestesiología, Reanimación y Terapia del Dolor, Complejo Hospitalario de Navarra, Pamplona, España.
Objectives: In fibroscopic intubation, the fact of achieving a direct view in real time does not guarantee the correct advance of the endotracheal tube (ET) to its intratracheal position. The use of oral cannulas helps in achieving a free airway in order to pass the fibroscope and the ET. This study compares the VAMA(®) (V) and Berman(®) (B) cannulas as regards the time required for the intubation, fibroscopic view, and the ease in positioning the ET.
View Article and Find Full Text PDFAn in vitro investigation of the effect of bevel design on the penetration and withdrawal forces of dental needles.
J Dent
February 2013
Centre for Oral Health Research, School of Dental Sciences, Newcastle University, Framlington Place, Newcastle Upon Tyne NE 2 4BW, UK.
Objectives: To compare the effect on insertion and withdrawal forces using needles with a standard atraumatic bevel to those with a novel asymmetrical bevel in vitro.
Methods: Maximum needle penetration forces were measured using a 10N load cell mounted on an Instron universal testing machine. Forces were determined during insertion through a 0.
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