The cardiovascular and gastrointestinal adverse effects of cyclooxygenase inhibitors seems to be a major concern that restricts their use in the treatment of urinary bladder dysfunction.

Cent European J Urol

Chair of Regenerative Medicine, Department of Tissue Engineering, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland ; Nicolaus Copernicus Hospital in Toruń, Department of General and Oncologic Urology, Toruń, Poland.

Published: April 2015

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408401PMC
http://dx.doi.org/10.5173/ceju.2015.01.e94DOI Listing

Publication Analysis

Top Keywords

cardiovascular gastrointestinal
4
gastrointestinal adverse
4
adverse effects
4
effects cyclooxygenase
4
cyclooxygenase inhibitors
4
inhibitors major
4
major concern
4
concern restricts
4
restricts treatment
4
treatment urinary
4

Similar Publications

mCNN-glucose: Identifying families of glucose transporters using a deep convolutional neural network based on multiple-scanning windows.

Int J Biol Macromol

January 2025

Department of Computer Science and Engineering, Yuan Ze University, Zhongli, Taoyuan 320315, Taiwan; Graduate program for Biomedical Informatics, Yuan Ze University, Zhongli, Taoyuan 320315, Taiwan. Electronic address:

Glucose transporters are essential carrier proteins that function on the phospholipid bilayer to facilitate glucose diffusion across cell membranes. The transporters play many physiological and pathological roles in addition to absorption and metabolism of fructose in food and the pathogenesis of gastrointestinal diseases. These carrier proteins play an important role in diseases of the nervous system, cardiovascular system, digestive system, and urinary system.

View Article and Find Full Text PDF

An Incidental Finding of Whipple's Disease Masquerading as Nonspecific, Long-Standing Symptoms.

Case Rep Infect Dis

December 2024

WakeMed's Division of Infectious Diseases, WakeMed Health and Hospitals, 3000 New Bern Ave, Raleigh 27610, North Carolina, USA.

Whipple's disease is a rare bacterial infection that is often present for years prior to diagnosis. Symptoms are nonspecific in the early stages of presentation and are primarily gastrointestinal in nature. The disease may progress with more systemic symptoms including arthralgia, fever, lymphadenopathy, cardiovascular disease, and central nervous system involvement.

View Article and Find Full Text PDF

Fetal Ascites: Its Prenatal Management and Postnatal Outcome.

J Obstet Gynaecol India

December 2024

Department of Fetal Medicine, Amrita Institute of Medical Sciences, Ponekkara, Kochi, Kerala 682041 India.

Objective: To report a single tertiary center experience in the management of prenatally diagnosed cases of fetal ascites and their postnatal outcomes.

Methods: Prenatally diagnosed fetal ascites cases were retrospectively analyzed from 2015 to 2022 using two-dimensional ultrasound with other investigations as required in a tertiary care center.

Results: Of 126 fetuses with fetal ascites, 70 progressed to hydrops and hence were excluded from the study.

View Article and Find Full Text PDF

The Young Doctors Program (YDP) is a "mini medical school" series for fifth-grade elementary children. The YDP was designed and led by medical students in the Academic Medicine and Leadership Track at the Rocky Vista University College of Osteopathic Medicine in Colorado. The curriculum of the program was designed around the State of Colorado Learning Standards with the purpose of educating students about emergencies and common ailments in five body systems (cardiovascular, respiratory, gastrointestinal, musculoskeletal, and renal) while also providing exposure to healthcare as a profession.

View Article and Find Full Text PDF

Introduction: Non-steroidal anti-inflammatory drugs are associated with severe gastrointestinal irritation upon prolonged use, largely due to their carboxylic (-- COOH) functional group.

Aim: To address this issue, we aimed to synthesize diclofenac conjugates with glucosamine and chitosan, converting the -COOH group into an amide (-CONH-) via a mechanochemical, environmentally friendly method.

Method: In this study, diclofenac acid was first converted to its acid chloride using thionyl chloride under mechanochemical conditions and subsequently reacted with glucosamine base and chitosan.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!