The division process used in a DFB diode laser-based optical gas sensor was studied to improve the immunity to laser power variation. Residual amplitude modulation (RAM) in wavelength modulation spectroscopy (WMS) detection was eliminated by intensity normalization using a division process. As a result the detected harmonic signals showed a significant improvement in line shape. For the first harmonic (1f) signal, Bias was improved from 38.7% to 1.2%; Baseline Difference was improved from 2.7% to 0.69% and Asymmetry was improved from 15.4% to 0.22%. For the second harmonic (2f) signal, the Asymmetry Coefficient was improved from 103% to 5.1%. Moreover the division process can further suppress the influence of unstable laser power. As a result, for the 1f signal, stable detection with a variation coefficient of 0.59% was obtained over a wide dynamic range (0.38-8.1 mW). For the 2f signal, stable detection with a variation coefficient of 0.53% was obtained from 0.64 mW to 8.27 mW. The test results showed a good agreement with the theoretical analysis and the proposed method has considerable potential application in gas sensing.
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http://dx.doi.org/10.3390/s150409582 | DOI Listing |
ACS Biomater Sci Eng
January 2025
Advanced Materials Department, Jožef Stefan Institute, 1000 Ljubljana, Slovenia.
Characterization and formation of the biomineral aragonite structures of the Noah's Ark shell ( L.,1758) were studied from structural, morphogenetic, and biochemical points of view. Structural and morphological features were examined using X-ray diffraction, field-emission scanning electron microscopy, and atomic force microscopy, while thermal properties were determined by thermogravimetric and differential thermal analyses.
View Article and Find Full Text PDFNeurology
February 2025
School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Background And Objectives: Lipid metabolism in older adults is affected by various factors including biological aging, functional decline, reduced physiologic reserve, and nutrient intake. The dysregulation of lipid metabolism could adversely affect brain health. This study investigated the association between year-to-year intraindividual lipid variability and subsequent risk of cognitive decline and dementia in community-dwelling older adults.
View Article and Find Full Text PDFSci Adv
January 2025
Division of Molecular Medicine, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.
Ketogenesis is a dynamic metabolic conduit supporting hepatic fat oxidation particularly when carbohydrates are in short supply. Ketone bodies may be recycled into anabolic substrates, but a physiological role for this process has not been identified. Here, we use mass spectrometry-based C-isotope tracing and shotgun lipidomics to establish a link between hepatic ketogenesis and lipid anabolism.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
February 2025
Department of Molecular Microbiology, Washington University in St. Louis, School of Medicine, St. Louis, MO 63130.
bradyzoites reside in tissue cysts that undergo cycles of expansion, rupture, and release to foster chronic infection. The glycosylated cyst wall acts as a protective barrier, although the processes responsible for formation, remodeling, and turnover are not understood. Herein, we identify a noncanonical chitinase-like enzyme TgCLP1 that localizes to micronemes and is targeted to the cyst wall after secretion.
View Article and Find Full Text PDFPLOS Glob Public Health
January 2025
Center for Global Health, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Humanitarian medical response to natural and human-made disasters can be complicated by high clinician, staff, and patient turnover. While electronic medical records are being scaled up globally, their use remains limited in humanitarian response settings. The Fast Electronic Medical Record (fEMR) system is an open-source electronic health record system specifically designed for use in resource-limited settings and humanitarian crises.
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